Evidence map›Paper›PMID 41367932›Full record

ReviewBioMed research international2025

Cervical Cancer in Women With HIV: A Call to Action for Equitable Prevention in Low- and Middle-Income Countries.

Jonathan Klutse, Yeena Abla Tay, Dzidzor Aku Attoh, Emmanuel Frimpong Gyekye, Charlotte Borteley Bortey, Esenam Dzifa Buatsi, Charlayne Cherylyn Oppong, Helena Lamptey, Collins Stephen Ahorlu, George Boateng Kyei and 1 more

Abstract readReview
In one paragraph

Review in BioMed research international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jonathan KlutseDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana, ug.edu.gh.ORCID https://orcid.org/0009-0003-8783-7283
Yeena Abla TayDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana, ug.edu.gh.ORCID https://orcid.org/0009-0000-0525-5617
Dzidzor Aku AttohDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana, ug.edu.gh.ORCID https://orcid.org/0009-0007-3220-7056
Emmanuel Frimpong GyekyeDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana, ug.edu.gh.ORCID https://orcid.org/0000-0002-7778-6748
Charlotte Borteley BorteyDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana, ug.edu.gh.
Esenam Dzifa BuatsiDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana, ug.edu.gh.ORCID https://orcid.org/0009-0007-4659-9679
Charlayne Cherylyn OppongDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana, ug.edu.gh.ORCID https://orcid.org/0009-0004-6332-9847
Helena LampteyDepartment of Immunology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana, ug.edu.gh.ORCID https://orcid.org/0000-0002-6426-6540
Collins Stephen AhorluDepartment of Epidemiology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana, ug.edu.gh.ORCID https://orcid.org/0000-0001-8116-3984
George Boateng KyeiDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana, ug.edu.gh.ORCID https://orcid.org/0000-0002-8678-4656
Evelyn Yayra BonneyDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana, ug.edu.gh.ORCID https://orcid.org/0000-0002-6634-8742

Funding

"Viral and latent HIV reservoir characteristics in HIV patients with persistent low-level viremiaR21AI174880 · NIAID · NOGUCHI MEMORIAL INSTITUTE / MEDICAL RES · PI BONNEY, EVELYN YAYRA · 2023 to 2024
$290k
NIAID NIH HHS R21 AI174880
6 · The paper itself

Abstract

Cervical cancer is preventable; however, it remains the leading cause of death in low- and middle-income countries (LMICs). Women with HIV (WWHs) have a sixfold higher risk of developing and dying from cervical cancer than women without HIV. Cervical cancer can be prevented by vaccination against high-risk human papillomaviruses (hrHPVs) and by screening for and treating precancer cervical lesions. While these preventive measures are routinely available to WWHs in developed countries, they are lacking in most LMICs, where the burden of HIV and cervical cancer is the highest. To prevent cervical cancer deaths among WWHs in LMICs, it is imperative to determine the dual burden of HIV and cervical cancer in LMICs. This narrative review synthesized scientific papers and policy documents on the intersection of HIV and cervical cancer in LMICs published between August 2006 and July 2025. We searched PubMed, Scopus, Web of Science, and Google Scholar for articles and official reports from the World Health Organization (WHO) and the US Centers for Disease Control and Prevention (CDC) on cervical cancer burden, prevention strategies, barriers, and outcomes among WWHs. Despite its proven effectiveness, HPV vaccination coverage in LMICs is under 30%, and screening uptake is below 20%. Weak health systems, workforce shortages, stigma, reliance on donor funding, and late-stage case presentation are major challenges in curbing cervical cancer in LMICs. Urgent political commitment is required to integrate precancer screening and HPV testing into routine HIV care and scale-up HPV vaccination to achieve the WHO's triple-intervention targets to eliminate cervical cancer among WWHs in LMICs.

Indexed as

HIV InfectionsUterine Cervical NeoplasmsDeveloping CountriesEarly Detection of CancerFemaleHumansPapillomavirus InfectionsPapillomavirus VaccinesPapillomavirus Vaccinescervical cancercervical cancer screeningHIVHPV DNAhuman papillomavirus

Identifiers

PMID41367932
PMCPMC12683070

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.