Evidence map›Paper›PMID 41368105›Full record

ArticleBiomedical optics express2025

Two-layer dynamic blood phantom for assessing NIRS device accuracy.

E Russomanno, X Yang, H Zohdi, J Jiang, M Ackermann, L Lanini, D Yacheur, M Wolf, A Kalyanov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

E RussomannoBiomedical Optics Research Laboratory (BORL), Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0009-0000-2206-3852
X YangD-ITET, ETH Zurich, Switzerland.
H ZohdiBiomedical Optics Research Laboratory (BORL), Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
J JiangBiomedical Optics Research Laboratory (BORL), Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-3983-7647
M AckermannBiomedical Optics Research Laboratory (BORL), Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
L LaniniBiomedical Optics Research Laboratory (BORL), Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
D YacheurBiomedical Optics Research Laboratory (BORL), Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
M WolfBiomedical Optics Research Laboratory (BORL), Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0001-7525-891X
A KalyanovBiomedical Optics Research Laboratory (BORL), Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-0246-6942

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Near-infrared spectroscopy (NIRS) is a widely used non-invasive method for measuring oxygenation and hemodynamics. NIRS devices are validated using phantoms that accurately replicate the optical properties of human tissue. The aim was to develop a multi-layer blood-lipid phantom specifically to mimic the layered anatomical structure of the human head. The phantom consists of two adjustable liquid layers, which model the optical properties and dynamic characteristics of brain and superficial tissues, together with two fixed solid layers. We demonstrate our phantom capabilities by testing the INVOS 7100 and Masimo O3 NIRS devices. The phantom enabled the Masimo instrument to show that it is less influenced by superficial changes (RMSE relative to superficial layer ∼50%) than the INVOS instrument (∼35%), highlighting better depth sensitivity. This shows the phantom's value as a tool for guiding device development and evaluation.

Identifiers

PMID41368105
PMCPMC12684046

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.