Trial reportLocal and regional anesthesia2025
Effect of External Oblique Intercostal Block on Postoperative Analgesia and Early Recovery in Patients Undergoing Open Liver Resection for Hepatocellular Carcinoma or Intrahepatic Bile Duct Stones: A Randomized Controlled Clinical Trial.
Trial report in Local and regional anesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: External oblique intercostal (EOI) block has recently emerged as a promising analgesic method for the upper abdominal surgery. This study aimed to assess the effect of EOI block on postoperative analgesia and early recovery following open liver resection (OLR). Patients and Methods: In this prospective, randomized, controlled trial, 64 patients scheduled for OLR were randomly allocated into EOI group and control group. EOI group received 30 mL of 0.25% ropivacaine bilaterally 30 min before induction of general anesthesia, whereas control group did not receive any block. The primary outcomes were sufentanil consumption 24 h after surgery. The secondary outcomes mainly included: the visual analogue scale (VAS) pain scores at rest and on coughing at 2, 12, 24, 48 h postoperatively; number of analgesia pump compression 24 h postoperatively; quality of recovery-15 (QoR-15) scale score 48 h after surgery; Pittsburgh sleep quality index (PSQI) score the first night postoperatively; and plasma levels of norepinephrine (NE), cortisol (Cor), high mobility group box protein 1 (HMGB1), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) 1h before surgery and 6 h postoperatively. Results: A total of 60 patients had completed the study (n = 30 per group). Sufentanil consumption 24 h postoperatively in EOI group was less than that in control group (mean difference: 4.45 μg, 95% CI, 1.6-7.2, Conclusion: EOI block given to patients undergoing OLR could provide effective postoperative analgesia, enhance the quality of postoperative recovery, and attenuate postoperative stress and inflammation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.