Evidence map›Paper›PMID 41368585›Full record

ReviewFrontiers in pharmacology2025

Overcoming the blood-brain barrier: targeted delivery strategies for gliomas.

Xue Du, Chunbao Chen, Yijun Zeng, Zhinei Lin

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xue DuDepartment of Oncology and Hematology, The 3RD Affiliated Hospital of Chengdu Medical College, Chengdu Pidu District People's Hospital, Chengdu, China.
Chunbao ChenDepartment of Neurosurgery, The 3RD Affiliated Hospital of Chengdu Medical College, Chengdu Pidu District People's Hospital, Chengdu, China.
Yijun ZengDepartment of Neurosurgery, The 3RD Affiliated Hospital of Chengdu Medical College, Chengdu Pidu District People's Hospital, Chengdu, China.
Zhinei LinDepartment of Oncology and Hematology, The 3RD Affiliated Hospital of Chengdu Medical College, Chengdu Pidu District People's Hospital, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurological gliomas, as the most common and deadly primary brain tumors, face two major therapeutic obstacles: the blockade of the blood-brain barrier (BBB) and high tumor heterogeneity. In recent years, research on novel drug delivery systems has brought hope for glioma treatment. This article elaborates on the research progress of novel drug delivery systems in glioma treatment, including various nanocarriers, targeted delivery strategies, and gene therapy drug delivery systems. It analyzes their advantages and challenges, outlooks future development directions, and aims to provide a reference for optimizing drug delivery systems for glioma therapy.

Indexed as

blood-brain barrierblood-tumor barrierdrug delivery systemsnanocarriersneurological gliomatargeted therapy

Identifiers

PMID41368585
PMCPMC12682902

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.