Evidence map›Paper›PMID 41368977›Full record

ArticleExperimental physiology2026

The effect of artificial gravity on the outcome of a two-week resistance vibration exercise programme: BRAVE study.

Igor B Mekjavic, Riccardo G Sorrentino, Jack Fortune, Jason T Fisher, Lydia Tsoutsoubi, Leonidas G Ioannou, Andrej Vovk, Matej Supej, Adam C McDonnell, Urša Ciuha

Abstract read
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Igor B MekjavicDepartment of Automatics, Biocybernetics, and Robotics, Jožef Stefan Institute, Ljubljana, Slovenia.ORCID https://orcid.org/0000-0001-5930-2159
Riccardo G SorrentinoDepartment of Automatics, Biocybernetics, and Robotics, Jožef Stefan Institute, Ljubljana, Slovenia.
Jack FortuneDepartment of Automatics, Biocybernetics, and Robotics, Jožef Stefan Institute, Ljubljana, Slovenia.
Jason T FisherDepartment of Automatics, Biocybernetics, and Robotics, Jožef Stefan Institute, Ljubljana, Slovenia.
Lydia TsoutsoubiDepartment of Automatics, Biocybernetics, and Robotics, Jožef Stefan Institute, Ljubljana, Slovenia.
Leonidas G IoannouDepartment of Automatics, Biocybernetics, and Robotics, Jožef Stefan Institute, Ljubljana, Slovenia.
Andrej VovkDepartment of Clinical Physiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Matej SupejFaculty of Sport, University of Ljubljana, Ljubljana, Slovenia.
Adam C McDonnellDepartment of Automatics, Biocybernetics, and Robotics, Jožef Stefan Institute, Ljubljana, Slovenia.ORCID https://orcid.org/0000-0003-3898-1759
Urša CiuhaDepartment of Automatics, Biocybernetics, and Robotics, Jožef Stefan Institute, Ljubljana, Slovenia.

Funding

European Space Agency 4000138718/22/NL/DBSlovene Research and Innovation Agency P2-0076
6 · The paper itself

Abstract

We evaluated the feasibility and efficacy of a 2-week training programme comprising resistance vibration exercise (RVE) without and with artificial gravity (AG). Participants (n = 24) were divided into three groups: (i) URVE: upright loaded squat exercise; (ii) HRVE: horizontal loaded squat exercise; and (iii) AGRVE: loaded squat exercise conducted on a short-arm human centrifuge. All participants followed the same protocol and were exposed to the same ground reaction force, whilst performing exercise comprising bilateral squats, triple extension squats and single/bilateral calf raises. Before and after the 2-week training period, we measured thigh and calf muscle strength with isokinetic dynamometry, muscular power with a jump test, volume with functional muscle magnetic resonance imaging, and body composition with dual-energy X-ray absorptiometry. All groups showed significant improvements in eight-repetition maximum squat strength (P < 0.0001, G > 0.80), whilst only the AGRVE group demonstrated a small effect in jump height (G = 0.26). The AGRVE group significantly increased knee extension and flexion maximum voluntary contraction (MVC), with no comparable changes in the HRVE or URVE groups. The AGRVE group increased total thigh muscle volume (P = 0.03), with notable hypertrophy in the vastus medialis, semitendinosus, and vastus intermedius muscles. These findings demonstrate that AGRVE is significantly superior to HRVE and URVE in enhancing knee MVC and thigh muscle volume, thus indicating that artificial gravity improves the outcome of resistance vibration exercise in ambulatory participants.

Indexed as

ExerciseGravity, AlteredMuscle, SkeletalResistance TrainingVibrationAdultBody CompositionFemaleHumansMagnetic Resonance ImagingMaleMuscle ContractionMuscle StrengthThighYoung Adultexercise physiologygravitymuscle strength

Identifiers

PMID41368977
PMCPMC12949193

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.