Evidence map›Paper›PMID 41369297›Full record

ArticleClinical transplantation2025

The Role of Albuminuria in Diagnosing and Stratifying Kidney Disease in Heart Transplant Recipients: A KDIGO Criteria-Based Analysis.

Pedro Caravaca-Pérez, Anthony Salazar Rodriguez, José Jesús Broseta, Eduard Solé Gonzalez, María Ángeles Castel, Juan José Rodriguez, Elena Cuadrado-Payán, Diana Rodriguez-Espinosa, Elena Sandoval, Aleix Cases and 2 more

Abstract read
In one paragraph

Article in Clinical transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Pedro Caravaca-PérezHeart Failure and Heart Transplant Unit, Institut Clínic Cardiovascular (ICCV), Hospital Clínic, Universitat De Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0001-9362-8371
Anthony Salazar RodriguezHeart Failure and Heart Transplant Unit, Institut Clínic Cardiovascular (ICCV), Hospital Clínic, Universitat De Barcelona, Barcelona, Spain.
José Jesús BrosetaInstitut D'investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.ORCID https://orcid.org/0000-0002-4559-9083
Eduard Solé GonzalezHeart Failure and Heart Transplant Unit, Institut Clínic Cardiovascular (ICCV), Hospital Clínic, Universitat De Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0002-5727-9925
María Ángeles CastelHeart Failure and Heart Transplant Unit, Institut Clínic Cardiovascular (ICCV), Hospital Clínic, Universitat De Barcelona, Barcelona, Spain.
Juan José RodriguezHeart Failure and Heart Transplant Unit, Institut Clínic Cardiovascular (ICCV), Hospital Clínic, Universitat De Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0001-6289-3658
Elena Cuadrado-PayánInstitut D'investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.ORCID https://orcid.org/0000-0003-2412-6911
Diana Rodriguez-EspinosaInstitut D'investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.ORCID https://orcid.org/0000-0002-1027-7156
Elena SandovalInstitut D'investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.ORCID https://orcid.org/0000-0002-4242-5133
Aleix CasesInstitut D'investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.ORCID https://orcid.org/0000-0002-6962-8184
Ana García-ÁlvarezHeart Failure and Heart Transplant Unit, Institut Clínic Cardiovascular (ICCV), Hospital Clínic, Universitat De Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0002-1718-2424
Marta FarreroHeart Failure and Heart Transplant Unit, Institut Clínic Cardiovascular (ICCV), Hospital Clínic, Universitat De Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0002-2404-8821

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is a common but poorly characterized complication in heart transplant (HT) recipients due to limited use of renal damage markers, such as albuminuria. Our aim is to determine CKD prevalence based on the Kidney Disease Improving Global Outcomes (KDIGO) criteria, assess CKD risk stratification according KDIGO guidelines, and describe the use of cardiorenal protective drugs in a contemporary HT cohort.

methodsA cross-sectional, single-center study was conducted in stable HT recipients under follow-up in 2023. CKD was defined as an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73m

resultsAmong 207 patients (median age 65 years; 29% women; median time since transplant: 8 years), the median eGFR was 51 mL/min/1.73m

conclusionsCKD is highly prevalent in HT recipients, with UACR improving diagnostic accuracy. Over half of patients fell into high-risk KDIGO categories, indicating substantial CKD severity. However, the underuse of renal-protective therapies highlights the need for better alignment with current clinical guidelines.

Indexed as

AlbuminuriaBiomarkersHeart TransplantationPostoperative ComplicationsPractice Guidelines as TopicRenal Insufficiency, ChronicAgedCross-Sectional StudiesFemaleFollow-Up StudiesGlomerular Filtration RateHumansMaleMiddle AgedPrevalencePrognosisBiomarkersalbuminuriachronic kidney diseaseheart transplantation

Identifiers

PMID41369297
PMCPMC12693005

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.