Evidence mapPaperPMID 41369334Full record

ArticleCells2025

Purinergic-Mediated Calcium Signaling in Quiescent and Activated Hepatic Stellate Cells: Evidence That P2Y1 Receptor Delays Activation.

Esperanza Mata-Martínez, Ana Patricia Juárez-Mercado, Adriana González-Gallardo, José David Núñez-Ríos, Mauricio Díaz-Muñoz, Rolando Hernández-Muñoz, Francisco G Vázquez-Cuevas

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Esperanza Mata-MartínezDepartamento de Biología Celular y Desarrollo, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City CP 04510, Mexico.ORCID 0000-0002-0457-7558
Ana Patricia Juárez-MercadoDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro CP 76230, Mexico.
Adriana González-GallardoUnidad de Proteogenómica, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro CP 76230, Mexico.
José David Núñez-RíosDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro CP 76230, Mexico.ORCID 0009-0008-3557-9442
Mauricio Díaz-MuñozDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro CP 76230, Mexico.ORCID 0000-0002-9019-8246
Rolando Hernández-MuñozDepartamento de Biología Celular y Desarrollo, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City CP 04510, Mexico.ORCID 0000-0002-5010-775X
Francisco G Vázquez-CuevasDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro CP 76230, Mexico.

Funding

PAPIIT-DGAPA-UNAM-México IN202253 and IN207224SECIHTI-México CBF2023-2024-200
6 · The paper itself

Abstract

Hepatic stellate cells (HSC) play a crucial role in the fibrotic response of the liver when they transdifferentiate from quiescent cells (qHSC) to myofibroblast (MFB). Ca

Indexed as

Calcium SignalingHepatic Stellate CellsReceptors, Purinergic P2Y1Adenosine TriphosphateAnimalsCalciumMaleMiceMice, Inbred C57BLMyofibroblastsAdenosine TriphosphateCalciumReceptors, Purinergic P2Y1adenine/uridine nucleotideshepatic stellate cells activationintracellular calcium dynamicsP2Y1 receptorphenotypic transdifferentiationpurinergic receptors

Identifiers

PMID41369334
PMCPMC12691116

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.