Evidence mapPaperPMID 41369375Full record

ReviewCells2025

New Evidence in Male Infertility Diagnosis: The Role of Metabolomics.

Giuseppina Peluso, Marco Serrao, Lidia Urlandini, Vittoria Rago, Saveria Aquila, Adele Vivacqua

Abstract readReview
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giuseppina PelusoSperm Bank, Department of Maternal Infant, A.O. of Cosenza, 87100 Cosenza, Italy.ORCID 0000-0002-8102-2126
Marco SerraoDepartment of Urology, Tirrenia Hospital, 87021 Belvedere Marittimo, Italy.
Lidia UrlandiniDepartment of Pharmacy and Health and Nutrition Sciences, University of Calabria, 87030 Rende, Italy.
Vittoria RagoDepartment of Pharmacy and Health and Nutrition Sciences, University of Calabria, 87030 Rende, Italy.ORCID 0000-0003-3971-7378
Saveria AquilaDepartment of Pharmacy and Health and Nutrition Sciences, University of Calabria, 87030 Rende, Italy.ORCID 0000-0003-4738-6927
Adele VivacquaDepartment of Pharmacy and Health and Nutrition Sciences, University of Calabria, 87030 Rende, Italy.ORCID 0000-0001-5333-8396

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male infertility affects a significant proportion of couples struggling to conceive and re-quire a comprehensive investigation into the underlying causes and potential diagnostic markers. Seminal biomarkers and multi-omic approaches, particularly metabolomics, have provided valuable insights into the alterations of molecular pathways associated with male infertility. This review systematically integrates literature, focusing on studies which examine the interaction between seminal biomarkers, metabolomics, and various omics technologies in the evaluation of sperm quality, and then male infertility. We high-light the importance of a multi-dimensional approach to decipher the complex etiology of male infertility and identify potential diagnostic markers.

Indexed as

Infertility, MaleMetabolomicsBiomarkersHumansMaleSemenSpermatozoaBiomarkersmale fertilitymetabolomic analysissemen biomarkerssperm quality

Identifiers

PMID41369375
PMCPMC12691394

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.