Evidence map›Paper›PMID 41369803›Full record

ReviewHeart failure reviews2025

Chronic kidney disease following left ventricular assist device implantation: contemporary insights and future perspectives.

Ingrid Alvarez-Echeverry, Goksel Guven, Parsa Jahangiri, Dennis A Hesselink, Osama Soliman, Indranee Rajapreyar, J Eduardo Rame, Can Ince, Kadir Caliskan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Heart failure reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ingrid Alvarez-EcheverryDepartment of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Goksel GuvenDepartment of Intensive Care, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Parsa JahangiriDepartment of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Dennis A HesselinkInternal Medicine, Division of Nephrology and Transplantation, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Osama SolimanDepartment of Cardiology, Galway University Hospital, Galway, Ireland.
Indranee RajapreyarDepartment of Clinical Cardiology at Jefferson Heart Institute, Philadelphia, USA.
J Eduardo RameDepartment of Clinical Cardiology at Jefferson Heart Institute, Philadelphia, USA.
Can InceDepartment of Intensive Care, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Kadir CaliskanDepartment of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. dr.kcaliskan@outlook.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decade, an increasing number of left ventricular assist devices (LVADs) have been implanted to treat patients with end-stage heart failure. Although LVAD therapy improves hemodynamics and survival, it is also associated with potentially life-threatening complications. A common and significant complication following LVAD implantation is chronic kidney disease (CKD), which is associated with high morbidity and mortality. Despite improvements in kidney function early after LVAD implantation, creatinine levels return to pre-implantation levels or higher in the long term. With the increasing number of LVAD implantations in the last decades, it is essential to focus on LVAD-associated CKD in order to improve the outcomes of LVAD therapy. In addition, identifying potential markers for early diagnosis may optimize perioperative management and prevent disease progression, which may now be the only realistic therapeutic option. This review describes the definition, diagnosis, incidence, pathophysiology, and risk factors for CKD after LVAD implantation. Additionally, future perspectives on the prevention and management of CKD in LVAD patients are discussed.

Indexed as

Heart-Assist DevicesHeart FailureRenal Insufficiency, ChronicDisease ProgressionHumansIncidenceRisk FactorsChronic kidney diseaseKidney dysfunctionLeft ventricular assist deviceLVADState-of-the-art review

Identifiers

PMID41369803
PMCPMC12696148

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.