ArticleAbdominal radiology (New York)2026
Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma of the liver: clinical features, imaging findings and potential diagnostic clues.
Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
objectiveEpstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma (EBV MATERIALS AND
methodsClinical and imaging data from patients with histopathologically confirmed hepatic EBV
resultsEleven patients (8 males, 3 females; median age: 38 years; range: 21 - 58 years) with 13 lesions were included. Most patients lacked hepatitis B infection (9/11, 81.8%), and elevated absolute eosinophil counts were noted in 54.5% (6/11). Lesion diameters ranged from 12 - 154 mm. On B-mode, lesions larger than 5 cm (4/5, 80.0%) exhibited patchy hyperechoic areas with a Luffa-Reticulum Sign. On CEUS, most lesions displayed rapid hyperenhancement, accompanied by early (< 45 s) "washout" (6/9, 66.7%). Perfluorobutane-enhanced CEUS demonstrated Kupffer-phase defects in all cases (5/5, 100.0%). On CE-MRI, most lesions exhibited heterogeneous hyperenhancement in the arterial phase, while the majority showed iso- or hypointensity in the portal venous and delayed phases. On gadoxetate-enhanced CE-MRI, lesions displayed hypointense signals during transitional- and hepatobiliary-phase (8/8, 100.0%). Notably, characteristic features included capsule appearances (6/12, 50.0%) and targetoid features (8/12, 66.7%).
conclusionsHepatic EBV
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