Evidence map›Paper›PMID 41370416›Full record

ArticleJBRA assisted reproduction2025

Heat exposure modulates redox balance and gonadal-related hormones in Wistar rats.

Damilare Emmanuel Rotimi, Akinbowale Ewaoluwa Shalom, Oluyomi Stephen Adeyemi

Abstract read
In one paragraph

Article in JBRA assisted reproduction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Damilare Emmanuel RotimiDepartment of Biochemistry, Landmark University, Omu-Aran 251101, Nigeria.
Akinbowale Ewaoluwa ShalomDepartment of Biochemistry, Landmark University, Omu-Aran 251101, Nigeria.
Oluyomi Stephen AdeyemiDepartment of Biochemistry, Medicinal Biochemistry & Toxicology Laboratory, Bowen University, Iwo 232101, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study assessed the effect of heat exposure on gonadal-related hormones in male and female Wistar rats.

methodsTwenty rats (140 - 160) were divided into 2 groups (male and female rats) and further sub-grouped into control and heat-exposed rats. Rats were exposed to heat for 4 hours daily for 21 days after which the rats were necropsied, and blood collected from the jugular veins.

resultsHeat exposure caused appreciable decreases in the levels of luteinizing hormones and follicle-stimulating hormones in both the male and female rats., Also, heat exposure caused a decline in the level of testosterone in male rats and decreased progesterone and oestrogen in their female counterparts. Furthermore, heat exposure caused oxidative stress by elevating the levels of malondialdehyde and nitric oxide, but lowering the antioxidants such as catalase, superoxide dismutase and thiols in rats.

conclusionsThis study thus showed that heat exposure significantly disrupts hormonal balance and induces oxidative stress in both male and female Wistar rats. Findings have implications for climate change impact on health.

Indexed as

Hot TemperatureOxidative StressAnimalsFemaleFollicle Stimulating HormoneLuteinizing HormoneMaleOxidation-ReductionProgesteroneRatsRats, WistarTestosteroneFollicle Stimulating HormoneLuteinizing HormoneProgesteroneTestosteroneclimate changeglobal warmingreproductive toxicologythermal stress

Identifiers

PMID41370416
PMCPMC12694987

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.