ArticleNature communications2025
Computational whole-body-exposome models for global precision brain health.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Trial
- Toward the prevention of clinically manifest Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Genetic-exposome interactions and aging clocks in dementia: the ReDLat2 initiative.Nature medicine · 2026Article
- Suboptimal adherence to brain health recommendations in patients pursuing anti-amyloid antibody therapy for Alzheimer's disease: Report from the Brain Health Vital Signs project.The journal of prevention of Alzheimer's disease · 2026Article
- Linking the exposome to the brain-behaviour phenotype.Nature reviews. Neuroscience · 2026Review
- Music as a scientific metaphor for mind and brain.Neuroscience and biobehavioral reviews · 2026Review
- Nanotechnology-enhanced Natural Products for Cancer Chemoprevention: Molecular Mechanisms and Clinical Translation.The AAPS journal · 2026Review
- The exposome of brain aging across 34 countries.Nature medicine · 2026Article
- Value drivers and barriers to the adoption of Precision Psychiatry in Latin America: a qualitative study.BMC psychiatry · 2026Article
- Contextualizing Blood-Based Biomarkers for Dementia Globally.Journal of neurochemistry · 2026Review
- Scientific knowledge about dementia: From the Global South to the world.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Childhood adversities and the exposome in dementia risk and brain health.Current opinion in psychiatry · 2026Review
- Expotype-phenotype resilience and multimodal aging clocks.Clinical and translational medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors.
Funding
Abstract
The worldwide rise of neurological and psychiatric conditions poses major challenges. However, current global research remains fragmented, dominated by limited cohorts and poorly integrated datasets that disconnect whole-body health, exposome, and brain health. Theories rarely unify brain measures with extracerebral factors or capture heterogeneity in individual trajectories. We introduce multimodal diversity, a non-linear, non-simplistic causal and ecological construct integrating data representation, whole-body and exposomic factors, and computational modeling to address this situated, embedded, and embodied complexity. This heuristic metamodel integrates global, multilevel data into personalized predictions fostering population inclusion, multimodal integration, diagnostic precision, and equitable, context-sensitive advances in brain health.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.