ReviewAnnals of intensive care2025
Applied physiology at the bedside: using invasive blood pressure as a true monitoring tool.
Review in Annals of intensive care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Twenty-five years of septic shock hemodynamic resuscitation trials: a conceptual perspective.Critical care (London, England) · 2026Review
- Beyond the arterial line: less, more, or smarter use?Critical care (London, England) · 2026Article
- Cardiac output and determinants.Intensive care medicine · 2026Article
- Clarifying physiology-guided subphenotyping of hypotension in early sepsis.Annals of intensive care · 2026Article
- Comparison between invasive radial and femoral arterial pressures and carotid tonometry in ICU patients: A physiological study.Annals of intensive care · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Invasive arterial blood pressure (BP) monitoring is a cornerstone of hemodynamic assessment in critically ill patients. This review explores how the individual components of BP-systolic arterial (SAP), diastolic arterial (DAP), mean arterial (MAP), and pulse pressure (PP)-offer valuable insights into cardiovascular physiology and can be leveraged as real-time therapeutic tools in intensive care settings. A strong emphasis is placed on the technical requirements for accurate BP waveform interpretation and the physiological meaning of each BP component. PP is examined as a surrogate for stroke volume and a dynamic marker of fluid responsiveness, particularly in mechanically ventilated patients. DAP is discussed as a reflection of vasomotor tone, with clinical implications for guiding the initiation of vasopressors. The concept of diastolic shock index (DSI) and the newly proposed VNERi ratio (DAP/[Heart rate × norepinephrine dose]) are introduced as potentially superior markers for assessing vascular tone and vasopressor responsiveness, respectively. These indices may facilitate earlier identification of patients requiring escalation of vasopressor therapy, including the initiation of vasopressin in addition to norepinephrine. The review advocates for a physiology-driven, individualized approach to hemodynamic management, using invasive BP not merely as a safety parameter but as an actionable guide for precision resuscitation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.