Evidence map›Paper›PMID 41373403›Full record

ArticleInternational journal of molecular sciences2025

Generation of Induced Pluripotent Stem Cells and Neuroepithelial Stem Cells from a Family with the Pathogenic Variant p.Q337X in Progranulin.

Katarzyna Gaweda-Walerych, Adam Figarski, Sylwia Gawlik-Zawiślak, Marta Woźniak, Anna Chołoniewska, Natalia Mierzwa, Eliza Lutostańska, Jakub Szymanowski, Michalina Wężyk

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katarzyna Gaweda-WalerychDepartment of Neurogenetics and Functional Genomics, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0000-0001-8670-1200
Adam FigarskiDepartment of Neurogenetics and Functional Genomics, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0000-0001-7513-7157
Sylwia Gawlik-ZawiślakDepartment of Genetics, Institute of Psychiatry and Neurology, Sobieskiego 9, 02-957 Warsaw, Poland.ORCID 0000-0003-4973-6433
Marta WoźniakDepartment of Genetics, Institute of Psychiatry and Neurology, Sobieskiego 9, 02-957 Warsaw, Poland.
Anna ChołoniewskaDepartment of Neurogenetics and Functional Genomics, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0000-0003-4178-2566
Natalia MierzwaDepartment of Neurogenetics and Functional Genomics, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0009-0000-1452-3230
Eliza LutostańskaDepartment of Neurogenetics and Functional Genomics, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Jakub SzymanowskiLaboratory of Advanced Microscopy Techniques (LAMT), Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Michalina WężykDepartment of Neurogenetics and Functional Genomics, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0000-0001-7498-4610

Funding

EU Joint Program Neurodegenerative Disease Research (EU JPND; JPco-fuND2) 2021/03/Y/NZ5/00112Medical Research Agency 2024/ABM/03/KPO/KPOD.07.07-IW.07-0105/24-00
6 · The paper itself

Abstract

Pathogenic

Indexed as

Frontotemporal DementiaInduced Pluripotent Stem CellsNeural Stem CellsNeuroepithelial CellsProgranulinsCell DifferentiationCell LineFemaleFibroblastsHumansMaleMiddle AgedMutationPedigreeGRN protein, humanProgranulinsembryoid bodyfrontotemporal dementia (FTD)GRNinduced pluripotent stem cells (iPSCs)neuroepithelial stem cells (NES)pluripotency markersprogranulin

Identifiers

PMID41373403
PMCPMC12692286

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.