SynthesisInternational journal of molecular sciences2025
Crude Plant Extracts and Their Anti-Inflammatory Potential in Oral Inflammatory Cell Models: A Systematic Review of In Vitro Studies.
Synthesis in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- From Sea to Cell:Marine drugs · 2026Article
- Chemical Compositions, Traditional Applications, and Biological Activities ofMolecules (Basel, Switzerland) · 2026Review
- Awareness and intended behavioral responses to oral potentially malignant disorders: an image-based assessment among dental clinic attendees in Jordan.BMC oral health · 2026Article
- Chemical Profiling, Analgesic and Anti-Inflammatory Activities ofPlants (Basel, Switzerland) · 2026Article
- In vitro and in vivo antibacterial activities and phytochemical screening of 80% methanol extract from Ehretia cymosa leaves.PloS one · 2026Article
- Melissa officinalis extract selectively suppresses STAT1 signaling in oral epithelial cells.Frontiers in immunology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants are a rich source of bioactive compounds with broad pharmaceutical potential, particularly for their anti-inflammatory properties. Oral inflammation underlies many local and systemic diseases, yet conventional anti-inflammatory drugs have adverse effects. Crude plant extracts offer promising, safer alternatives. This systematic review synthesizes evidence on the anti-inflammatory activity of whole plant extracts in vitro oral models of inflammation. It also highlights methodological considerations for improved reproducibility. PubMed searches following PRISMA guidelines identified studies using oral or periodontal cells stimulated with relevant inflammatory triggers and treated with crude plant extracts. Extracts from
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.