Evidence map›Paper›PMID 41373441›Full record

ReviewInternational journal of molecular sciences2025

GAMT Deficiency: Clinical Presentation, Treatment, Diagnosis, Animal Models, Preclinical and Clinical Developments.

Sara Biagiotti, Elena Perla, Serafina Manila Guzzo, Manuela Tolve, Francesca Nardecchia, Luigia Rossi, Claudia Carducci, Tiziana Pascucci, Vincenzo Leuzzi, Mauro Magnani

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sara BiagiottiDepartment of Biomolecular Sciences, University of Urbino, 61029 Urbino, Italy.ORCID 0000-0001-9554-7858
Elena PerlaDepartment of Biomolecular Sciences, University of Urbino, 61029 Urbino, Italy.ORCID 0009-0004-8588-7276
Serafina Manila GuzzoDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-6120-2824
Manuela TolveClinical Pathology Unit, AOU Policlinico Umberto I, 00161 Rome, Italy.ORCID 0000-0003-0263-4325
Francesca NardecchiaDepartment of Human Neurosciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-0808-2827
Luigia RossiDepartment of Biomolecular Sciences, University of Urbino, 61029 Urbino, Italy.
Claudia CarducciDepartment of Experimental Medicine, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-0515-9208
Tiziana PascucciDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-1520-7373
Vincenzo LeuzziDepartment of Human Neurosciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-2314-6139
Mauro MagnaniDepartment of Biomolecular Sciences, University of Urbino, 61029 Urbino, Italy.ORCID 0000-0001-6456-6626

Funding

NextGenerationEU, PRIN 2022 PNRR M4.C2.1.1 P202284WZH
6 · The paper itself

Abstract

Guanidinoacetate Methyl Transferase (

Indexed as

AtaxiaGuanidinoacetate N-MethyltransferaseLanguage Development DisordersMovement DisordersAnimalsCreatineDisease Models, AnimalHumansMiceCreatineGuanidinoacetate N-Methyltransferasecreatine deficiencydiagnosticsGAMT deficiencyGAMT genemetabolic disordermolecular pathology

Identifiers

PMID41373441
PMCPMC12692480

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.