Evidence map›Paper›PMID 41373992›Full record

ArticleNutrients2025

The Effectiveness of Nutritional Interventions on Maternal and Childhood Anaemia in Sindh, Pakistan.

Khizar Ashraf, Michael J Dibley, Javeria Ikram, Muhammad Umer, Gul Nawaz Khan, Imran A Chauhadry, Shabina Ariff, Tanvir M Huda, Sajid B Soofi

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Khizar AshrafSydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0009-0007-2872-9564
Michael J DibleySydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-1554-5180
Javeria IkramSouth Western Sydney Local Health District, Liverpool, NSW 2170, Australia.ORCID 0009-0008-4643-6412
Muhammad UmerCentre of Excellence in Women & Child Health, The Aga Khan University, Karachi 74800, Pakistan.ORCID 0000-0002-8976-1687
Gul Nawaz KhanCentre of Excellence in Women & Child Health, The Aga Khan University, Karachi 74800, Pakistan.ORCID 0000-0002-2466-1693
Imran A ChauhadryCentre of Excellence in Women & Child Health, The Aga Khan University, Karachi 74800, Pakistan.ORCID 0000-0001-7425-3113
Shabina AriffCentre of Excellence in Women & Child Health, The Aga Khan University, Karachi 74800, Pakistan.ORCID 0000-0002-9627-2662
Tanvir M HudaSydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-8996-4361
Sajid B SoofiCentre of Excellence in Women & Child Health, The Aga Khan University, Karachi 74800, Pakistan.ORCID 0000-0003-4192-8406

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesIn Pakistan, 41.7% of women of reproductive age and 53.7% of children aged 6-59 months are anaemic. This study aimed to evaluate the effectiveness of a nutritional supplementation programme, underpinned with behaviour change communication and implemented through Lady Health Workers (LHWs), in reducing anaemia among pregnant and lactating women as well as 6-59-month-old children.

methodsThis study used a quasi-experimental design with an intervention and a control group. A total of 2821 and 2410 pregnant and lactating women and 3397 and 3277 children aged 6-59 months participated in the baseline and endline surveys, respectively. The study areas were matched for demographic and economic characteristics, and both had routine public-sector health and nutrition programmes, including iron-folic acid supplementation during pregnancy. The participants in the intervention group received additional nutritional support. Throughout the pregnancy and in the first six months of exclusive breast feeding, women were provided 5 kg (165 g/day) of wheat soya blend (WSB) per month. Children aged 6-23 months received lipid-based nutrient supplements (LNS), and those aged 24-59 months received micronutrient powder. We applied a difference-in-difference (DID) analysis with kernel propensity score matching to assess the impact on anaemia, a secondary outcome of a stunting prevention programme.

resultsMaternal anaemia (both pregnant and breastfeeding women) declined substantially in the intervention areas from 80.4% to 62.6% compared with a smaller reduction in the control areas (80.0% to 72.9%). The DID estimate showed a 10.7-percentage-point (pp) greater decline in maternal anaemia (

conclusionsOverall, the findings suggest that LHWs can effectively reduce maternal anaemia when iron-folic acid supplementation is complemented with WSB and targeted behaviour change communication.

Indexed as

AnemiaDietary SupplementsAdultBreast FeedingChild, PreschoolFemaleHumansInfantMaleMaternal Nutritional Physiological PhenomenaMicronutrientsPakistanPregnancyYoung AdultMicronutrientsbehaviour change communicationchildhood anaemialipid-based nutrient supplementsmaternal anaemianutritionPakistanprogrammatic reviewWHO anaemia framework

Identifiers

PMID41373992
PMCPMC12694230

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.