Evidence map›Paper›PMID 41374990›Full record

ReviewCancers2025

Neurofibromatosis Type 1: Genetic Mechanisms and Advances in Therapeutic Innovation.

Yuqing Lu, Manzhu Xu, Xiaojun Chen, Huazhen Xu, Nihao Sun, Karis E Weisgerber, Ren-Yuan Bai

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuqing LuKennedy Krieger Institute, 707 N Broadway, Baltimore, MD 21205, USA.ORCID 0009-0007-2641-2555
Manzhu XuKennedy Krieger Institute, 707 N Broadway, Baltimore, MD 21205, USA.ORCID 0000-0001-7587-1992
Xiaojun ChenKennedy Krieger Institute, 707 N Broadway, Baltimore, MD 21205, USA.ORCID 0009-0007-9098-1680
Huazhen XuKennedy Krieger Institute, 707 N Broadway, Baltimore, MD 21205, USA.
Nihao SunDepartment of Biomedical Engineering, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA.ORCID 0009-0006-2177-0081
Karis E WeisgerberKennedy Krieger Institute, 707 N Broadway, Baltimore, MD 21205, USA.ORCID 0000-0003-0760-1725
Ren-Yuan BaiKennedy Krieger Institute, 707 N Broadway, Baltimore, MD 21205, USA.ORCID 0000-0001-5281-9091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in the

Indexed as

AAV-based gene therapychimeric antigen receptor T cell (CAR-T) therapyGAP-related domain (GRD)malignant peripheral nerve sheath tumors (MPNSTs)MEK inhibitorneurofibromatosis type 1 (NF1)neurofibrominNF1 geneoncolytic herpes simplex virus (oHSV) therapyplexiform neurofibromas (pNFs)

Identifiers

PMID41374990
PMCPMC12691366

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.