Evidence map›Paper›PMID 41375037›Full record

ReviewCancers2025

New Treatment Options for Pancreatic Neuroendocrine Tumors: A Narrative Review.

Agnieszka Romanowicz, Marta Fudalej, Alicja Asendrych-Woźniak, Anna Badowska-Kozakiewicz, Paweł Nurzyński, Andrzej Deptała

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Agnieszka RomanowiczDepartment of Oncology, National Medical Institute of the Ministry of the Interior and Administration, 02-507 Warsaw, Poland.
Marta FudalejDepartment of Oncology, National Medical Institute of the Ministry of the Interior and Administration, 02-507 Warsaw, Poland.ORCID 0000-0001-8665-2875
Alicja Asendrych-WoźniakDepartment of Oncology, National Medical Institute of the Ministry of the Interior and Administration, 02-507 Warsaw, Poland.
Anna Badowska-KozakiewiczDepartment of Oncological Propaedeutics, Medical University of Warsaw, 01-445 Warsaw, Poland.
Paweł NurzyńskiDepartment of Oncology, National Medical Institute of the Ministry of the Interior and Administration, 02-507 Warsaw, Poland.
Andrzej DeptałaDepartment of Oncology, National Medical Institute of the Ministry of the Interior and Administration, 02-507 Warsaw, Poland.ORCID 0000-0003-2640-2043

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic neuroendocrine neoplasms (PanNENs) are a diverse group of cancers with varying clinical presentations and prognoses due to differences in morphology and clinical stage. Most are non-functional tumors that express somatostatin receptors (SSTRs). Several treatment options have been established for patients with locally advanced or metastatic PanNETs, but the optimal choice of treatment approach and the sequence of available therapies are not yet clearly defined and are currently being studied in multiple ongoing clinical trials. Additionally, new drugs are being researched for PanNET treatment, including immune checkpoint inhibitors, next-generation peptide receptor radionuclide therapy, and other targeted biological therapies. To improve treatment outcomes for patients with PanNETs, a multidisciplinary team should evaluate systemic treatment options. The aim of this article is to review currently available therapies and discuss new and emerging systemic treatment strategies for patients with advanced PanNETs.

Indexed as

immunotherapynarrative reviewpancreatic neuroendocrine tumorspeptide receptor radionuclide therapytargeted therapy

Identifiers

PMID41375037
PMCPMC12691000

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.