Evidence map›Paper›PMID 41375112›Full record

ArticleMolecules (Basel, Switzerland)2025

Anti-Neuroinflammatory Effects of Compounds Isolated from

Hwan Lee, Yezhi Jin, Ji-Ae Hong, Chenyang Bai, Gyoyoung Lee, Suhyeon Woo, Chi-Su Yoon, Donghyuck Bae, Dong-Sung Lee

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hwan LeeNatural Resources Laboratory, Green Bio Headquarters, Jeonnam Bio Foundation (JBF), Jangheung-gun 59338, Jeollanam-do, Republic of Korea.ORCID 0000-0001-5015-5949
Yezhi JinResearch Institute of Pharmaceutical Sciences (RIPS), College of Pharmacy, Chosun University, Dong-gu, Gwangju 61452, Jeollanam-do, Republic of Korea.
Ji-Ae HongNatural Resources Laboratory, Green Bio Headquarters, Jeonnam Bio Foundation (JBF), Jangheung-gun 59338, Jeollanam-do, Republic of Korea.
Chenyang BaiResearch Institute of Pharmaceutical Sciences (RIPS), College of Pharmacy, Chosun University, Dong-gu, Gwangju 61452, Jeollanam-do, Republic of Korea.
Gyoyoung LeeResearch Institute of Pharmaceutical Sciences (RIPS), College of Pharmacy, Chosun University, Dong-gu, Gwangju 61452, Jeollanam-do, Republic of Korea.
Suhyeon WooInstitute of Pharmaceutical Research and Development, College of Pharmacy, Wonkwang University, Iksan 54538, Jeollabuk-do, Republic of Korea.
Chi-Su YoonInstitute of Pharmaceutical Research and Development, College of Pharmacy, Wonkwang University, Iksan 54538, Jeollabuk-do, Republic of Korea.
Donghyuck BaeNatural Resources Laboratory, Green Bio Headquarters, Jeonnam Bio Foundation (JBF), Jangheung-gun 59338, Jeollanam-do, Republic of Korea.
Dong-Sung LeeResearch Institute of Pharmaceutical Sciences (RIPS), College of Pharmacy, Chosun University, Dong-gu, Gwangju 61452, Jeollanam-do, Republic of Korea.ORCID 0000-0002-9234-7567

Funding

This study was conducted with the support of the R&D program for Forest ScienceTechnology (project no. RS-2023-KF002467) provided by Korea Forest Service (Korea Forestry Promotion In-stitute). project no. RS-2023-KF002467
6 · The paper itself

Abstract

Aging is a major risk factor for neurodegenerative diseases in which microglia-driven neuroinflammation plays a critical role in neuronal dysfunction and disease progression. In this study, we sought to isolate bioactive metabolites from

Indexed as

Anti-Inflammatory AgentsFruitMicrogliaNF-kappa BPlant ExtractsQuercusSignal TransductionAnimalsCell LineCyclooxygenase 2Interleukin-6LipopolysaccharidesMiceNitric Oxide Synthase Type IIAnti-Inflammatory AgentsCyclooxygenase 2Interleukin-6LipopolysaccharidesNF-kappa BNitric Oxide Synthase Type IIPlant ExtractsBV2 microglianatural compoundsneuro-inflammationNF-κBQuercus acuta

Identifiers

PMID41375112
PMCPMC12693635

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.