Evidence mapPaperPMID 41375166Full record

ArticleMolecules (Basel, Switzerland)2025

In Vitro and In Silico Analyses Explore the Role of Flavonoid Classes in the Antiviral Activity of Plant Extracts Against the Dengue Virus.

Sindi A Velandia, Elena E Stashenko, Elizabeth Quintero-Rueda, Sergio Conde-Ocazionez, Lady J Sierra, Raquel E Ocazionez

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sindi A VelandiaResearch Center for Chromatography and Mass Spectrometry (CROM-MASS), Universidad Industrial de Santander, Carrera 27, Calle 9, Bucaramanga 680002, Colombia.ORCID 0000-0001-8953-6124
Elena E StashenkoResearch Center for Chromatography and Mass Spectrometry (CROM-MASS), Universidad Industrial de Santander, Carrera 27, Calle 9, Bucaramanga 680002, Colombia.ORCID 0000-0001-7052-932X
Elizabeth Quintero-RuedaResearch Center for Chromatography and Mass Spectrometry (CROM-MASS), Universidad Industrial de Santander, Carrera 27, Calle 9, Bucaramanga 680002, Colombia.
Sergio Conde-OcazionezNetherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, UMC Location University of Amsterdam, 1105 BA Amsterdam, The Netherlands.ORCID 0000-0002-8290-5502
Lady J SierraResearch Center for Chromatography and Mass Spectrometry (CROM-MASS), Universidad Industrial de Santander, Carrera 27, Calle 9, Bucaramanga 680002, Colombia.
Raquel E OcazionezResearch Center for Chromatography and Mass Spectrometry (CROM-MASS), Universidad Industrial de Santander, Carrera 27, Calle 9, Bucaramanga 680002, Colombia.

Funding

Ministry of Science, Technology and Innovation Grant 679 RCFP44842-212-2018
6 · The paper itself

Abstract

This study examined the relationship between flavonoid content and the antiviral effects of plant extracts against the dengue virus (DENV). Fourteen extracts from medicinal plants cultivated in Colombia, which were prepared by ultrasonic-assisted solvent extraction (UAE) and supercritical fluid extraction (SFE) were included. UHPLC/ESI-Q-Orbitrap-MS analysis identified forty-six flavonoids. Antiviral effect on viral adsorption was evaluated using the DENV-CPE-based assay. UAE extracts of

Indexed as

Antiviral AgentsDengue VirusFlavonoidsPlant ExtractsComputer SimulationHumansMolecular Docking SimulationPlants, MedicinalScutellariaAntiviral AgentsFlavonoidsPlant Extractsantiviral activitydengue virusin silico analysisLippia albaLippia origanoidesScutellaria coccinea

Identifiers

PMID41375166
PMCPMC12693615

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.