Evidence map›Paper›PMID 41375209›Full record

ArticleMolecules (Basel, Switzerland)2025

A Stereospecific Synthesis and In Vitro Anti-Influenza H1N1 Properties of Lithocholic Acid-Based

Irina Smirnova, Alexander Lobov, Liana Zakirova, Dmitriy Polovyanenko, Irina Bagryanskaya, Vladimir Zarubaev, Oxana Kazakova

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Irina SmirnovaUfa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences, 71, pr. Oktyabrya, 450054 Ufa, Russia.ORCID 0000-0001-7176-505X
Alexander LobovUfa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences, 71, pr. Oktyabrya, 450054 Ufa, Russia.ORCID 0000-0002-9223-508X
Liana ZakirovaUfa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences, 71, pr. Oktyabrya, 450054 Ufa, Russia.ORCID 0000-0001-5143-8836
Dmitriy PolovyanenkoN. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences (SB RAS), 630090 Novosibirsk, Russia.ORCID 0009-0000-3835-825X
Irina BagryanskayaN. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences (SB RAS), 630090 Novosibirsk, Russia.ORCID 0000-0001-7760-5540
Vladimir ZarubaevExperimental Virology Laboratory, Department of Virology, St. Petersburg Pasteur Institute of Epidemiology and Microbiology, 14 Mira St., 197001 St. Petersburg, Russia.ORCID 0000-0002-5224-3771
Oxana KazakovaUfa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences, 71, pr. Oktyabrya, 450054 Ufa, Russia.ORCID 0000-0002-5606-1588

Funding

Russian Science Foundation 25-23-00668
6 · The paper itself

Abstract

Bile acids provide a versatile platform for the design of biologically active compounds due to their amphiphilic structure, biocompatibility, and capacity for diverse chemical modifications. Among them, lithocholic acid is a promising scaffold for designing and revealing new antiviral agents. A novel lithocholic acid-based 3-

Indexed as

Antiviral AgentsInfluenza A Virus, H1N1 SubtypeLithocholic AcidSpiro CompoundsAnimalsCrystallography, X-RayDogsHumansInfluenza, HumanMadin Darby Canine Kidney CellsMicrobial Sensitivity TestsMolecular StructureStructure-Activity RelationshipAntiviral AgentsLithocholic AcidSpiro Compounds1,2,4-trioxolaneADMEanti-viralbile acidsGriesbaum co-ozonolysislithocholic acidPASS predictionX-ray analysis

Identifiers

PMID41375209
PMCPMC12693687

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.