Synthesis of Bioconjugation Reagents for Use in Covalent Cross-Linking of Proteins by Azide-Alkyne Cycloaddition.

Nadja Suhorepec, Luka Ciber, Uroš Grošelj, Nejc Petek, Bogdan Štefane, Marko Novinec, Jurij Svete

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nadja SuhorepecFaculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia.

Luka CiberFaculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia.

Uroš GrošeljFaculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia.ORCID 0000-0002-5186-9879

Nejc PetekFaculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia.ORCID 0000-0003-3331-4885

Bogdan ŠtefaneFaculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia.ORCID 0000-0002-8709-9853

Marko NovinecFaculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia.ORCID 0000-0003-1824-1649

Jurij SveteFaculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia.ORCID 0000-0003-3339-3595

Funding

The Slovenian Research and Innovation Agency I0-0022The Slovenian Research and Innovation Agency N1-0211The Slovenian Research and Innovation Agency P1-0179

6 · The paper itself

Abstract

A series of azide- and cyclooctyne-functionalized

Indexed as

AlkynesAzidesCross-Linking ReagentsCycloaddition ReactionProteinsSerum Albumin, BovineAnimalsCattleClick ChemistryFluorescent DyesAlkynesAzidesCross-Linking ReagentsFluorescent DyesProteinsSerum Albumin, Bovineamidationazide-alkyne cycloadditionbenzotriazolidesfluorescein dyesprotein cross-linking

Identifiers

PMID41375219

DOI10.3390/molecules30234623

PMCPMC12693261

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.