Evidence map›Paper›PMID 41376190›Full record

ArticleVeterinary and comparative oncology2026

A Comparative Study of Melanocytic Tumours: Linking Portuguese Dogs and Cats to Human Cases.

Catarina Alves Pinto, Ana Isabel Ribeiro, João Niza-Ribeiro, Carlos Alberto Palmeira de Sousa, Katia Pinello, Andreia Alexandra Ferreira Santos

Abstract readComparative Study
In one paragraph

Article in Veterinary and comparative oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Catarina Alves PintoDepartment of Veterinary Clinics, ICBAS-School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal.ORCID https://orcid.org/0000-0002-1465-7666
Ana Isabel RibeiroDepartamento de Geografia, Faculdade de Letras da Universidade do Porto, Centro de Estudos em Geografia e Ordenamento do Território (CEGOT), Porto, Portugal.
João Niza-RibeiroLaboratório Para a Investigação Integrativa e Translacional em Saúde Populacional (ITR), Porto, Portugal.
Carlos Alberto Palmeira de SousaExperimental Pathology and Therapeutics Research Group of the Research Center of IPO-Porto, Porto, Portugal.
Katia PinelloLaboratório Para a Investigação Integrativa e Translacional em Saúde Populacional (ITR), Porto, Portugal.
Andreia Alexandra Ferreira SantosDepartment of Veterinary Clinics, ICBAS-School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal.

Funding

Fundação Para a Ciência e a Tecnologia 2023.04484.BDFundação Para a Ciência e a Tecnologia CEECIND/02386/2018Fundação Para a Ciência e a Tecnologia LA/P/0064/2020Fundação Para a Ciência e a Tecnologia UID/00776/2025Fundação Para a Ciência e a Tecnologia UIDB/04084/2025Fundação Para a Ciência e a Tecnologia UIDB/04750/2020Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto
6 · The paper itself

Abstract

Melanocytic tumours (MT) occur in both humans and companion animals, presenting an opportunity for comparative oncology research. Thus, this study provides a comprehensive epidemiological analysis comparing MT in Portuguese dogs, cats and humans. Data were obtained from the Portuguese National Cancer Registry (RON) (2011-2021) and Vet-OncoNet (2020-2023), utilising standardised oncological classification systems (ICD-O-3.2 and Vet-ICD-O-canine-1). The results indicate that Melanoma was the most frequently diagnosed MT across all three species, while melanocytomas were common in dogs but rare in cats and humans. A higher incidence rate (IR) for MT was observed in dogs (IR = 16.1) compared to humans (IR = 8.1) and cats (IR = 6.3), and neutered dogs (10.8 years) were diagnosed at significantly older ages than intact ones (9.9 years). Shar-Peis (RR = 14.2, p < 0.001) had the highest RR compared to mixed-breed dogs, followed closely by Rhodesian Ridgebacks (RR = 12.2, p < 0.001) and Golden Retrievers (RR = 6.4, p < 0.001). Spatial analysis revealed significant clustering of MT cases in humans and dogs, with a strong geographical overlap (BLISA = 0.345, p < 0.001) in urban regions. This study provides the first epidemiological comparison of MT in these three species in Portugal, underscoring the sentinel role of companion animals in human oncology and the relevance of comparative oncology in translational cancer research.

Indexed as

Cat DiseasesDog DiseasesMelanomaSkin NeoplasmsAnimalsCatsDogsFemaleHumansIncidenceMalePortugalcatcomparative oncologydogepidemiologygeographic distributionhumanmelanocytic tumours

Identifiers

PMID41376190
PMCPMC12875750

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.