Evidence mapPaperPMID 41376233Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2025

Adjuvant therapy with Traditional Chinese Medicine and glycemic control in patients with type 2 diabetes mellitus: a retrospective cohort study.

Shang Chang, Liu Ping, Han Junge, Zeng Shuanghui, Wang Yue, Han Mei, Sun Luying

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Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Shang ChangDepartment of Nephropathy and Endocrine, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100010, China.
Liu PingDepartment of Nephropathy and Endocrine, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100010, China.
Han JungeDepartment of Nephropathy and Endocrine, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100010, China.
Zeng ShuanghuiDepartment of Nephropathy and Endocrine, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100010, China.
Wang YueDepartment of Nephropathy and Endocrine, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100010, China.
Han MeiDepartment of Nephropathy and Endocrine, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100010, China.
Sun LuyingDepartment of Nephropathy and Endocrine, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100010, China.

Funding

Industry-University-Research Collaborative Project: the Clinical and Basic Research on Liuzi Yangshen Formula in Preventing and Treating Renal Tubular Injury HX-DZM-202501
6 · The paper itself

Abstract

objectiveTo explore the association between adjuvant therapy with Traditional Chinese Medicine (TCM) and glycemic control in patients with type 2 diabetes mellitus (T2DM) in the real world.

methodsIn this retrospective cohort study, we consecutively collected medical records of T2DM patients enrolled in the Metabolic Management Center (MMC) from October 2021 to April 2024. Patients were divided into two groups based on the presence or absence of a TCM prescription within 6 months after enrollment in MMC management. Propensity score matching (PSM) was used to balance the differences in covariates between the two groups. The independent efficacy of adjuvant TCM therapy on glycemic control was assessed by univariate and multivariate logistic regression, and then further determined by subgroup analysis.

resultsA total of 580 patients were included, with 441 patients (76.0%) receiving TCM treatment. Before PSM, multivariable logistic regression revealed that adjuvant TCM therapy was significantly associated with a lower incidence of poor glycemic control [odds ratio (

conclusionThe adjuvant TCM therapy is beneficial for achieving optimal glycemic control, suggesting that adjuvant TCM therapy may be embraced as a viable glycemic management approach for T2DM patients with poor glycemic control.

Indexed as

Diabetes Mellitus, Type 2Drugs, Chinese HerbalMedicine, Chinese TraditionalAdultAgedBlood GlucoseFemaleGlycemic ControlHumansMaleMiddle AgedRetrospective StudiesBlood GlucoseDrugs, Chinese Herbaldiabetes mellitus, type 2drugs, Chinese herbalglycemic controlmedicine, Chinese traditionalmetabolic management center

Identifiers

PMID41376233
PMCPMC12703843

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.