Evidence map›Paper›PMID 41376250›Full record

ArticleImmunology and cell biology2026

The changing immune landscape of innate-like T cells and other innate cells throughout life.

Marziyeh Taheri, Christopher Menne, Jeremy Anderson, Louis Perriman, Shuo Li, Stuart P Berzins, Paul V Licciardi, Thomas M Ashhurst, Sedigheh Jalali, Daniel G Pellicci

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunology and cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marziyeh TaheriMurdoch Children's Research Institute, Melbourne, VIC, Australia.
Christopher MenneMurdoch Children's Research Institute, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0003-2211-8766
Jeremy AndersonMurdoch Children's Research Institute, Melbourne, VIC, Australia.
Louis PerrimanMurdoch Children's Research Institute, Melbourne, VIC, Australia.
Shuo LiMurdoch Children's Research Institute, Melbourne, VIC, Australia.
Stuart P BerzinsDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
Paul V LicciardiMurdoch Children's Research Institute, Melbourne, VIC, Australia.
Thomas M AshhurstSydney Cytometry Core Research Facility, The University of Sydney and Centenary Institute, Sydney, NSW, Australia.ORCID https://orcid.org/0000-0001-7269-7773
Sedigheh JalaliMurdoch Children's Research Institute, Melbourne, VIC, Australia.
Daniel G PellicciMurdoch Children's Research Institute, Melbourne, VIC, Australia.

Funding

CSL Centenary FellowshipNational Health and Medical Research Council 2030186Sylvia & Charles Viertel Fellowship
6 · The paper itself

Abstract

Spectral flow cytometry is an advanced immunological tool that can enable comprehensive analysis of the immune system by simultaneously comparing innate and adaptive immune cells. Here, using a 40-color antibody panel, we advance our knowledge of innate-like cells by investigating chemokine receptors and maturation markers not usually assessed on these populations, examining age-related effects on these immune cell subsets. We characterize phenotypic changes of peripheral blood mononuclear cells (PBMCs) in three age groups: newborns (cord blood), adults aged 20-30 years, and adults aged > 70 years. We compare the age-related changes of innate cells, including ILCs, NK cells, monocytes, dendritic cells, and innate-like T cells, comparing them with memory T cells. We also examine subsets of CD4

Indexed as

AgingImmunity, InnateT-LymphocytesT-Lymphocyte SubsetsAdultAgedBiomarkersDendritic CellsFemaleHumansImmunophenotypingInfant, NewbornKiller Cells, NaturalMaleMiddle AgedYoung AdultBiomarkersagingCD markersimmunophenotypinginnate cellsinnate‐like T cellsspectral flow cytometry

Identifiers

PMID41376250
PMCPMC12800730

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.