ArticleNutrition research and practice2025
Diabetes-specific oral nutritional supplement for prediabetes improves postprandial glycemic responses: an open-label, crossover clinical trial.
Article in Nutrition research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
BACKGROUND/
objectivesRegulating the postprandial glucose levels is crucial for preventing the progression of prediabetes to diabetes. This study examined the effects of a diabetes-specific nutrition formula (DSNF) on the postprandial plasma glucose, serum insulin, and serum c-peptide levels in individuals with prediabetes. SUBJECTS/
methodsAn open-label, crossover clinical trial was conducted to compare the effects of the DSNF versus standard oral nutritional supplement (ONS) on glycemic control. Fifteen subjects with prediabetes were enrolled and received the DSNF on the first visit and standard ONS on the second. The postprandial plasma glucose, serum insulin, and serum c-peptide incremental area under the curve (iAUC), as well as the incremental maximal concentration (iC
resultsAfter consuming the DSNF, the iAUC of the postprandial glucose level was significantly low compared to the standard ONS (1,683.49 ± 911.65 vs. 4,455.92 ± 1,658.77,
conclusionsThe consumption of DSNF significantly improved the postprandial glucose, insulin, and c-peptide responses compared to the standard ONS. Trial Registration: Clinical Research Information Service Identifier: KCT0008904.
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