Evidence map›Paper›PMID 41377639›Full record

ReviewHeart international2025

High-intensity Interval Versus Moderate-intensity Continuous Training in Heart Failure Rehabilitation: A Meta-analysis and Meta-regression.

Victor Joseph, Derren Rampengan, Stevanus Surya, Felicia Gunawan, Nathanael Tjipta, Juan Lele, Roy Novri Ramadhan, Starry Homenta Rampengan

Abstract readReview
In one paragraph

Review in Heart international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Victor JosephDepartment of Cardiology and Vascular Medicine, Faculty of Medicine, Sam Ratulangi University, Manado, North Sulawesi, Indonesia.
Derren RampenganFaculty of Medicine, Sam Ratulangi University, Manado, North Sulawesi, Indonesia.
Stevanus SuryaFaculty of Medicine, Udayana University, Bali, Denpasar, Indonesia.
Felicia GunawanFaculty of Medicine, Sam Ratulangi University, Manado, North Sulawesi, Indonesia.
Nathanael TjiptaFaculty of Medicine, Airlangga University, Surabaya, East Java, Indonesia.
Juan LeleFaculty of Medicine, Christian University of Indonesia, East Jakarta, Jakarta Capital Region, Indonesia.
Roy Novri RamadhanFaculty of Medicine, Airlangga University, Surabaya, East Java, Indonesia.
Starry Homenta RampenganDepartment of Cardiology and Vascular Medicine, Faculty of Medicine, Sam Ratulangi University, Manado, North Sulawesi, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Guidelines widely recommend exercise training as a complementary therapy for individuals with heart failure. While research highlights the potential of both high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT), a systematic review is required to solidify their effects on improving patients' oxygen uptake, functional capacity, cardiac function and quality of life (QoL). Objective: This meta-analysis aimed to compare the efficacy of HIIT and MICT on cardiopulmonary fitness, functional capacity, cardiac function and QoL among individuals with heart failure. Method: This review adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered in International Prospective Register of Systematic Reviews (PROSPERO; CRD42024602309). We searched PubMed, Cochrane Controlled Register of Trials (CENTRAL), Scopus, Web of Science, ProQuest, Embase, Google Scholar, PubMed Central (PMC), Elton B. Stephens Company (EBSCO) and Wiley. Risk of bias was assessed with the Revised Cochrane for Risk-Of-Bias Tool for Randomized Trials (RoB 2), and analyses were conducted in RStudio version 4.4.1. (Posit PBC, Massachusetts, USA) using the 'meta' package. Result: A total of 21 randomized controlled trials were included in the analysis. The overall quality assessment showed a low risk of bias. We found that the HIIT group is favourable in terms of cardiac function improvement, represented by left ventricular ejection fraction (LVEF; mean difference [MD]=2.69 [95% confidence interval (CI): 0.01, 5.38; p=0.0495]), peak oxygen uptake (peak VO Conclusion: HIIT appears to be more effective than MICT in improving functional capacity, such as LVEF, peak VO

Indexed as

cardiac rehabilitationendurance trainingExerciseheart failurehigh-intensity interval trainingmeta-analysismeta-regressionquality of lifesystematic review

Identifiers

PMID41377639
PMCPMC12687271

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.