ArticleFrontiers in medicine2025
An exploratory single arm study to evaluate the role of an Ayurvedic treatment protocol as a prerequisite for
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Ovarian reserve depicts the quality and quantity of oocytes remaining in the ovaries and gives an idea about ovarian function at a given time. Because of aging, ovarian reserve diminish physiologically. However, many women face a non-physiologic reduction of ovarian reserve, irrespective of age. To date, standard-of-care treatment options are not available to treat diminished ovarian reserve (DOR). Studies shows that DOR patients mostly undergo Materials and methods: An open label single arm trial will be conducted to explore the role of an Ayurveda treatment protocol as a prerequisite for IVF in women with DOR. Forty women diagnosed with DOR satisfying eligibility criteria will be recruited to the study. Out of them, thirty participants will be undergoing Ayurveda treatment prior to their next IVF, and ten participants will be assigned to control group for follicular fluid analysis. Within subject change in serum anti-mullerian hormone and antral follicle count will be the primary outcomes evaluated. The multiomics analysis of follicular fluid will be done in 20 participants recruited to the study (treatment group 10 and control group 10). Discussion: This multidisciplinary exploratory clinical trial will be the first study to explore the role of an Ayurvedic treatment protocol in managing DOR. The multi-omics approaches will be helpful in identifying potential biomarkers associated with treatment response. The information gained through the study might be useful in planning a safe and feasible pre-conception care for DOR patients undergoing IVF. Clinical trial registration: ctri.nic.in, identifier CTRI/2023/11/059872.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.