ArticleResearch square2025
Non-invasive electrical stimulation restores corneal nerve density and function in diabetic neuropathy via KCNN-dependent mechanism.
Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Diabetic neuropathy (DN) is the most common complication of diabetes mellitus (DM) and often involves the cornea, where progressive loss of nerve fibers contributes to impaired corneal sensitivity and wound healing defects. Current treatments are limited, underscoring the need for a regenerative therapy. Transcutaneous electrical stimulation (ES) is a neural modulating therapy that non-invasively delivers microcurrent electricity to the eye via orbital skin. ES treatment significantly restored the nerve density and sensory function in both streptozotocin-induced DM mice and
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