ReviewBiochemistry and biophysics reports2025
What role do miRNAs play in the injured heart of the infertile female?
Review in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A Review of microRNAs in the Post-transcriptional Regulation and its Clinical Manifestation in the Polycystic Ovary Syndrome.Reproductive sciences (Thousand Oaks, Calif.) · 2026Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to numerous overlapping risk factors between cardiovascular diseases (CVDs) and infertility, women of reproductive age with underlying CVD may increasingly seek reproductive assistance. miRNAs and exosomal miRNAs are well-known epigenetic modulators that regulate gene expression at the post-transcriptional level. A large body of evidence indicates the fundamental roles of various miRNAs in different aspects of both CVD and infertility. Dysregulation of miRNAs (including those carried by exosomes) could contribute to pathological alterations involved in CVD pathogenesis, potentially leading to female infertility-related disorders In particular, we emphasize how these miRNAs shape inflammatory, angiogenic and remodeling responses in the injured myocardium of infertile women. Herein, we review the roles of miRNAs in the development of CVD and female infertility. We also summarize recent research on the role of miRNAs in angiogenesis, including their targets and mechanisms of action. Understanding these mechanisms may facilitate the development of composite biomarkers and targeted diagnostic/therapeutic strategies for female infertility and cardiovascular disease, with a specific focus on myocardial injury.
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