Evidence mapPaperPMID 41378230Full record

ReviewFood science & nutrition2025

Beyond Thirst: Influence of Bicarbonate Mineral Water on Cardiovascular Risk Factors, Gastrointestinal Function, and Liver Health.

Katharina Mansouri, Maximilian Andreas Storz, Thierry Hanh, Andreas Hahn

Abstract readReview
In one paragraph

Review in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katharina MansouriInstitute of Food and One Health Leibniz University Hannover Hanover Germany.ORCID https://orcid.org/0009-0002-9867-2851
Maximilian Andreas StorzDepartment of Internal Medicine II, Center for Complementary Medicine, Medical Center, Faculty of Medicine University of Freiburg Freiburg Germany.ORCID https://orcid.org/0000-0003-3277-0301
Thierry HanhIndependent Researcher Paris France.
Andreas HahnInstitute of Food and One Health Leibniz University Hannover Hanover Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of diet in the modulation of systemic acid-base balance is of critical importance to human physiology. The contemporary dietary habits of the Western population, characterized by a high consumption of acid-forming foods such as meat and cheese, and a low intake of vegetables and fruits, have been associated with an elevated dietary acid load. This, in turn, has been linked to a range of adverse metabolic and cardiovascular consequences. To counteract these effects, it is important to consider dietary choices. Bicarbonate-rich mineral water offers an effective method to counteract diet-induced acid stress, showing positive effects on cardiovascular health, gastrointestinal function, and liver metabolism. The alkalizing effect of bicarbonate-rich mineral water can enhance insulin sensitivity through improved insulin receptor binding, resulting in an improvement in glycemic control. In terms of lipid metabolism, bicarbonate-rich mineral water may reduce cholesterol levels by altering intestinal conditions and increasing bile acid excretion. Both, effects on glucose and lipid metabolism may positively impact cardiovascular health. Despite the high sodium content of these waters, their effect on blood pressure remains mostly neutral or positive. Benefits also extend to individuals with gastrointestinal issues such as dyspepsia and heartburn, likely due to improved gastric motility and acid-buffering capacity. Overall, bicarbonate-rich mineral water represents a promising nonpharmacological strategy to reduce acid load and enhance metabolic, cardiovascular, and gastrointestinal health, although further research is necessary due to variations in study designs and water composition.

Indexed as

bicarbonatecardiovasculargastrointestinallivermineral water

Identifiers

PMID41378230
PMCPMC12687301

What Socratic holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.