Evidence map›Paper›PMID 41378320›Full record

ArticleAmerican journal of preventive cardiology2025

Global pattern, trend, and cross-country inequality of cardiovascular diseases caused by hypertension from 1990 to 2021, with projection from 2022 to 2060.

Xing Liu, Xiaoyang Wang, Yuxin Liang, Hongli Li, Jiazheng Chen, Zhijun Meng

Abstract read
In one paragraph

Article in American journal of preventive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xing LiuDepartment of Outpatient, Shanxi Provincial People's Hospital, Taiyuan, China.
Xiaoyang WangDepartment of Medical Technology, Shanxi Provincial People's Hospital, Shanxi Medical University, Taiyuan, China.
Yuxin LiangDepartment of Clinical Laboratory, Shanxi Provincial People's Hospital, Shanxi Medical University, Taiyuan, China.
Hongli LiDepartment of Clinical Laboratory, Shanxi Provincial People's Hospital, Shanxi Medical University, Taiyuan, China.
Jiazheng ChenSchool of the Fifth Clinical Medicine, Shanxi Medical University, Taiyuan, China.
Zhijun MengDepartment of Clinical Laboratory, Shanxi Provincial People's Hospital, Taiyuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular diseases caused by hypertension pose a serious threat to global health. This study analyzed trends and future projections of hypertension-related cardiovascular diseases burden using Global Burden of Disease 2021 data. Methods: We estimated mortality and disability-adjusted life years (DALYs) via DisMod-MR 2.1, analyzed regional disparities by socio-demographic index (SDI), and projected trends to 2060 using the Bayesian age-period-cohort model. Health inequalities were evaluated via the slope index of inequality and concentration index. Results: Globally, the number of DALYs and deaths due to cardiovascular diseases caused by hypertension increased in 2021, reaching 214,518,341 (95% uncertainty interval [UI]: 180,418,055-247,570,720) and 10,376,441 (95% UI: 8784,052-12,032,762) respectively, while the age-standardized DALYs rate (ASDR) and age-standardized mortality rate (ASMR) decreased. In high SDI regions, the number of DALYs and deaths decreased, while in the remaining regions, they increased. However, the ASDR and ASMR in all SDI regions decreased. In 21 major regions, the number of DALYs and deaths increased. East Asia had the highest values, and Oceania had the lowest. Only in Southern Sub-Saharan Africa did the ASDR and ASMR increase. Regarding age, DALYs rates increased with age from 15-74 years, and mortality increased with age from 15-84 years, and decreased after 75 and 85 years, respectively. It is predicted that DALYs rates and mortality continue to decline and stabilize by 2060. Conclusion: The burden of cardiovascular diseases caused by hypertension varies markedly across the globe, with declining rates in high SDI regions but rising trends in low and low-middle SDI regions. These findings indicate growing inequalities and the need for region-specific interventions.

Indexed as

Bayesian age-period-cohortCardiovascular diseasesGBDHealth inequality analysisHypertension

Identifiers

PMID41378320
PMCPMC12686654

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.