Evidence map›Paper›PMID 41378478›Full record

ArticleJournal of the American Heart Association2025

Household Aggregation of Hypertension in India: A Cross-Sectional Study of Nationally Representative Data From 450 000 Households.

Krishna Om Sanaka, Erica L Kocher, Nikhil Srinivasapura Venkateshmurthy, Nikhil Tandon, Shivani A Patel, Mohammed K Ali, Jithin Sam Varghese

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Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Krishna Om SanakaEmory College of Arts & Sciences Emory University Atlanta GA USA.
Erica L KocherNutrition and Health Sciences Doctoral Program, Laney Graduate School Emory University Atlanta GA USA.ORCID 0000-0001-7014-0576
Nikhil Srinivasapura VenkateshmurthyCenter for Chronic Disease Control New Delhi India.
Nikhil TandonDepartment of Endocrinology and Metabolism All India Institute of Medical Sciences New Delhi India.
Shivani A PatelEmory Global Diabetes Research Center of the Woodruff Health Sciences Center and Emory University Atlanta GA USA.ORCID 0000-0003-0082-5857
Mohammed K AliEmory Global Diabetes Research Center of the Woodruff Health Sciences Center and Emory University Atlanta GA USA.ORCID 0000-0001-7266-2503
Jithin Sam VargheseEmory Global Diabetes Research Center of the Woodruff Health Sciences Center and Emory University Atlanta GA USA.ORCID 0000-0003-3825-9897

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOver 315 million adults live with hypertension in India, of whom only 37% are diagnosed. In addition to community-based screening, targeting high-risk households may identify undiagnosed individuals. We estimated the magnitude of household aggregation of diagnosed and undiagnosed hypertension among co-residing adults and evaluated whether household members offer pathways for novel screening and management strategies. METHODS AND

resultsThe overall sample consisted of 450 520 households with 1 407 886 adult participants (18-99 years old) of the Indian National Family Health Survey-5, 2019 to 2021. Household aggregation was defined as ≥2 co-residing members of a household having hypertension (self-reported as physician diagnosed, or measured systolic blood pressure ≥140, or diastolic blood pressure ≥90 mm Hg). Among the analytic sample (mean age, 32.5 years; 53.2% women), 25.8% had hypertension, and 48.4% of respondents had ≥1 other members in the household with hypertension. Individuals with diagnosed (prevalence ratio [PR], 2.49 [95% CI, 2.44-2.54]) and undiagnosed hypertension (PR, 1.16 [95% CI, 1.15-1.17]) were more likely to cluster with others of the same status. Exploratory analyses suggest that the number of households to be screened to identify 1 new case of undiagnosed hypertension was lowest for households with a newly detected (ie, previously undiagnosed) individual with hypertension, followed by households of individuals with normal blood pressure and diagnosed hypertension, respectively.

conclusionsOur study provides novel evidence about aggregation of hypertension among Indian households. Given the high burden of hypertension in India, household-focused screening and management interventions can augment current strategies for closing the gaps in hypertension diagnosis and control.

Indexed as

Blood PressureFamily CharacteristicsHypertensionAdolescentAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHealth SurveysHumansIndiaMaleMass ScreeningMiddle AgedPrevalencefamilial clusteringglobal healthhigh blood pressurehousehold concordance

Identifiers

PMID41378478
PMCPMC12826902

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