Evidence map›Paper›PMID 41379057›Full record

ReviewJACC. Asia2026

Interconnected Pathways and Therapeutic Implications for Cardiovascular Aging and Diseases.

Xiaoyuan Bai, Yiyuan Zhang, Jing Qu, Guang-Hui Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in JACC. Asia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoyuan BaiBeijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yiyuan ZhangState Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Jing QuBeijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China; Aging Biomarker Consortium, Beijing, China. Electronic address: qujing@ioz.ac.cn.
Guang-Hui LiuBeijing Institute for Stem Cell and Regenerative Medicine, Beijing, China; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China; Aging Biomarker Consortium, Beijing, China; Advanced Innovation Center for Human Brain Protection, and National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing, China. Electronic address: ghliu@ioz.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, with their prevalence rising with advancing age. Progressive remodeling of the cardiovascular system during aging underlies increased vulnerability to cardiovascular pathologies. This review summarizes current insights into the structural, functional, and molecular hallmarks of both cardiovascular aging (CVA) and CVDs, highlighting their mechanistic convergence. By further discussing diagnostic biomarkers and intervention strategies that bridge these processes, we delineated the translational continuum linking CVA and CVDs. The understanding of their interconnections underscores the potential of targeting CVA as a strategy for CVD prevention, early diagnosis, and treatment.

Indexed as

biomarkercardiovascular agingcardiovascular diseasesinterventionmechanism

Identifiers

PMID41379057
PMCPMC12904831

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.