Evidence mapPaperPMID 41379582Full record

ArticleHuman vaccines & immunotherapeutics2025

Strategic positioning of immunization at the heart of Africa's health and development agenda.

Charles S Wiysonge, Duduzile Ndwandwe, Chinwe Iwu-Jaja, Chukwudi A Nnaji, Shingai Machingaidze, Abdu A Adamu, Andre Arsene Bita Fouda, Gregory D Hussey

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Charles S WiysongeCochrane South Africa, South African Medical Research Council, Cape Town, South Africa.ORCID 0000-0002-1273-4779
Duduzile NdwandweCochrane South Africa, South African Medical Research Council, Cape Town, South Africa.
Chinwe Iwu-JajaVaccine-Preventable Diseases Programme, World Health Organization Regional Office for Africa, Brazzaville, Congo.
Chukwudi A NnajiTechnical Department, Malaria Consortium, London, UK.
Shingai MachingaidzeAfrica Strategy and Engagement, Coalition for Epidemic Preparedness Innovations, London, UK.
Abdu A AdamuVaccine-Preventable Diseases Programme, World Health Organization Regional Office for Africa, Brazzaville, Congo.
Andre Arsene Bita FoudaVaccine-Preventable Diseases Programme, World Health Organization Regional Office for Africa, Brazzaville, Congo.
Gregory D HusseyVaccines for Africa Initiative, School of Public Health, University of Cape Town, Cape Town, South Africa.

Funding

World Health Organization 001
6 · The paper itself

Abstract

Immunization is one of the greatest public health achievements of all times, preventing millions of deaths and making major improvements in child survival in Africa. Beyond protecting against infectious diseases, vaccines foster educational attainment, productivity, and poverty reduction, while mitigating antimicrobial resistance and economic shocks. However, each year more than 9.5 million children in the World Health Organization African Region remain under-vaccinated, resulting in recurrent outbreaks of vaccine-preventable diseases. In 2024 alone, 59 outbreaks were reported across the region, including measles, variant polioviruses, meningitis, cholera, and yellow fever. To meet growing demands amid constrained resources, we propose three strategic shifts to reimagine immunization as a catalyst for resilient health systems and equitable development in Africa: (1) transitioning from vertical delivery models to integrated approaches embedded in primary health care; (2) expanding success metrics beyond coverage to include equity, resilience, and process indicators, supported by implementation science and digital innovations; and (3) reframing immunization as a whole-of-society development priority anchored in political leadership, sustainable financing, and regional vaccine manufacturing. By embracing these shifts, Africa can transform immunization into a driver of health system strengthening, equity, and sustainable development.

Indexed as

ImmunizationImmunization ProgramsVaccinationVaccine-Preventable DiseasesAfricaDisease OutbreaksHumansPublic HealthVaccinesVaccinesAfricaimmunizationimplementation scienceprimary health caresustainable financing

Identifiers

PMID41379582
PMCPMC12710898

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.