Evidence mapPaperPMID 41379723Full record

Trial reportHormone research in paediatrics2026

The Effectiveness of a Multidisciplinary, Personalized Lifestyle Intervention Program of Diet, Sleep and Physical Activity in the Management of Overweight and Obesity in Adolescence.

Aliki S Anastasiadou, Maria Manou, Sofia-Maria Genitsaridi, Sofia Iliada Karampatsou, Eleni Ramouzi, Athanasia Tragomalou, Athanasia Kyrkili, Stamatis Romas, Penio Kassari, Marina Papadopoulou and 1 more

Abstract readClinical Trial
In one paragraph

Trial report in Hormone research in paediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aliki S AnastasiadouDivision of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece.
Maria ManouDivision of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece.
Sofia-Maria GenitsaridiDivision of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece.
Sofia Iliada KarampatsouDivision of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece.
Eleni RamouziDivision of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece.
Athanasia TragomalouDivision of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece.
Athanasia KyrkiliDivision of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece.
Stamatis RomasDivision of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece.
Penio KassariDivision of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece.
Marina PapadopoulouDivision of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece.
Evangelia CharmandariDivision of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece, evangelia.charmandari@googlemail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: Overweight and obesity in adolescence represents a major health concern globally, owing to the associated increased morbidity and mortality in adulthood. The prevalence of overweight and obesity in adolescents in Greece is 41% and is the highest among European countries. The aim of our study was to assess the effectiveness of a multidisciplinary, personalized lifestyle intervention program of diet, sleep, and exercise in the management of overweight and obesity in adolescence.

methodsFive hundred and forty-four (544) adolescents (mean age ± standard deviation: 12.29 ± 2.10 years; 328 females, 216 males) were studied prospectively for 1 year. Participants were classified as having severe obesity (n = 192 35.3%), obesity (n = 107, 19.7%), overweight (n = 161, 29.6%), or normal body mass index (BMI) (n = 84, 15.4%) according to the International Obesity Task Force (IOTF) cut-off points. All subjects received multidisciplinary, personalized advice on diet, sleep, and exercise at frequent intervals for a period of 1 year. Detailed clinical evaluation and laboratory investigations were performed at the beginning and the end of the study.

resultsAdolescents with obesity and severe obesity had significantly higher systolic and diastolic blood pressure, as well as a more adverse cardiometabolic profile compared with their overweight and normal BMI counterparts. At the end of the study, obesity rates decreased by 15%, severe obesity rates by 33.8% and a significant improvement in most cardiometabolic risk factors was noted.

conclusionThese findings indicate that a multidisciplinary, personalized, lifestyle intervention program is effective at reducing the prevalence of overweight and obesity in adolescence. </p>.

Indexed as

DietExerciseLife StyleOverweightPediatric ObesitySleepAdolescentChildFemaleHumansMaleProspective StudiesAdolescenceDietObesityOverweightPhysical activitySleep

Identifiers

PMID41379723
PMCPMC12803520

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.