Evidence map›Paper›PMID 41379943›Full record

ArticleMMWR. Morbidity and mortality weekly report2025

Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025.

Stephanie A Irving, Elizabeth A K Rowley, Sean Chickery, Karthik Natarajan, Nicola P Klein, Shaun J Grannis, Toan C Ong, Sarah W Ball, Malini B DeSilva, Kristin Dascomb and 27 more

Abstract read
In one paragraph

Article in MMWR. Morbidity and mortality weekly report, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Vaccines for COVID-19: Effectiveness and value.Journal of managed care & specialty pharmacy · 2026
    Article
  3. Article
  4. Article
  5. Respiratory Virus Activity - United States, July 1, 2024-June 30, 2025.MMWR. Morbidity and mortality weekly report · 2026
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Stephanie A Irving
Elizabeth A K Rowley
Sean Chickery
Karthik Natarajan
Nicola P Klein
Shaun J Grannis
Toan C Ong
Sarah W Ball
Malini B DeSilva
Kristin Dascomb
Allison L Naleway
Melissa S Stockwell
Ashley B Stephens
Ousseny Zerbo
John Hansen
Lawrence Block
Karen B Jacobson
Brian E Dixon
Colin Rogerson
Tom Duszynski
Michelle A Barron
David Mayer
Catia Chavez
Zachary A Weber
Sarah E Reese
Inih Essien
Tamara Sheffield
Daniel Bride
Julie Arndorfer
Josh Van Otterloo
Padma Koppolu
Josephine Mak
Amber Kautz
Jennifer DeCuir
Ryan E Wiegand
Amanda B Payne
Ruth Link-Gelles

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During September 2023-August 2024, approximately 38,000 COVID-19-associated hospitalizations occurred among children and adolescents aged <18 years in the United States, a rate of approximately 53 per 100,000 children, ranging from 600 per 100,000 children aged <6 months to 21 per 100,000 children and adolescents aged 5-17 years. On June 27, 2024, the Advisory Committee on Immunization Practices recommended that all persons aged ≥6 months receive a 2024-2025 COVID-19 vaccine, which targeted Omicron JN.1 and JN.1-derived sublineages. Investigators used a test-negative case-control design to estimate vaccine effectiveness (VE) of 2024-2025 COVID-19 vaccines against COVID-19-associated emergency department or urgent care (ED/UC) visits during August 29, 2024-September 2, 2025, among immunocompetent children aged 9 months-4 years and children and adolescents aged 5-17 years in the CDC-funded Virtual SARS-CoV-2, Influenza, and Other respiratory viruses Network (VISION), a multisite electronic health record-based network in nine states. Among children aged 9 months-4 years, VE against COVID-19-associated ED/UC visits was estimated at 76% (95% CI = 58%-87%) during the first 7-179 days after vaccination. Among children and adolescents aged 5-17 years, VE against COVID-19-associated ED/UC visits was an estimated 56% (95% CI = 35%-70%) during the first 7-179 days after vaccination. These findings suggest that vaccination with a 2024-2025 COVID-19 vaccine dose provided children with additional protection against COVID-19-associated ED/UC encounters compared with no 2024-2025 dose.

Indexed as

COVID-19COVID-19 VaccinesVaccine EfficacyAdolescentCase-Control StudiesChildChild, PreschoolEmergency Service, HospitalFemaleHumansInfantMaleSARS-CoV-2United StatesCOVID-19 Vaccines

Identifiers

PMID41379943
PMCPMC12697930

What Socratic holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.