Trial reportNeurology(R) neuroimmunology & neuroinflammation2026
Trial report in Neurology(R) neuroimmunology & neuroinflammation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesWorking memory training (WMT) has been shown to improve WM in healthy older adults, patients with mild cognitive impairment, and individuals with HIV, including improvements in WM network efficiency. This randomized study explored near-transfer and far-transfer effects of WMT and examined whether
methodsParticipants were recruited from local communities. After screening and baseline evaluation, participants were randomized to either 25 sessions of adaptive or nonadaptive WMT (as an active control) over 5-8 weeks. Nontrained near-transfer WM tests, far-transfer tests, and self-reported executive functioning were performed at baseline, 1-month, and 6-month follow-ups. Genotyping included
resultsA total of 107 participants (60 with HIV, 47 SN) completed adaptive WMT, and 70 active controls (36 with HIV, 34 SN) completed nonadaptive WMT. Overall, 96 adaptive WMT participants and 68 active controls completed the 1-month follow-up while 77 adaptive WMT participants and 37 active controls completed the 6-month follow-up. Adaptive WMT led to higher improvement indices in SN participants than in the HIV group (training*HIV serostatus: DISCUSSION: Adaptive WMT improved near-transfer WM, far-transfer performance, and self-reported executive functioning in all participants, but more sustained effects among participants with HIV. These findings suggest that adaptive WMT can be an effective adjunctive therapy for cognitive deficits in PWH, especially in those with CLASSIFICATION OF EVIDENCE: This study provides Class IV evidence that adaptive WMT improves near-transfer WM, far-transfer performance, and self-reported executive functioning in patients with or without HIV, regardless of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.