ArticleEuropean journal of medical research2025
Influence of axial length and myopia severity on the achieved optical zone in KLEx surgery: a pilot study.
Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
purposeKeratorefractive lenticule extraction (KLEx) is widely used for myopia correction. This study aims to investigate the relationships among the designed lenticular area (DLA), lenticule stretched preparation (LSP), and the achieved functional optical zone (AFOZ) to identify factors influencing these discrepancies.
settingThe study was conducted at the Eye & ENT Hospital of Fudan University, Shanghai.
designThe study was a non-randomized, prospective analysis of patients' surgical parameters.
methods29 young adults who underwent KLEx for myopia correction were included. Preoperative data, including spherical equivalent and axial length, were recorded. The removed lenticule was stained, flattened, and measured using ImageJ software to calculate the LSP area. Postoperative AFOZ was assessed using Pentacam topography. Statistical analysis compared LSP, DLA, and AFOZ and correlated differences with clinical parameters.
resultsThe mean age of the patients was 23.07 ± 4.76 years, with a median spherical equivalent of - 4.3755.375, (- 5.375, - 3.188) D. The AFOZ was smaller than the DLA (35.26 (35.260, 35.260) mm
conclusionsAnatomical factors such as axial length and myopia severity affect the AFOZ in KLEx. Future research should incorporate additional biomechanical and imaging parameters to enhance the accuracy of outcome predictions.
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