Evidence mapPaperPMID 41383194Full record

ArticleAnnals of cardiothoracic surgery2025

Clinical and echocardiographic outcomes of patients with mitral annular calcification undergoing mitral valve surgery: a 10-year single center experience.

Rahul Kanade, Jack Gosden, Jonathan Roland, Mohamed Aly, Maximilian Reisinger, Mateusz Kachel, Luigi Pirelli, Koji Takeda, Michael Argenziano, Hiroo Takayama and 4 more

Abstract read
In one paragraph

Article in Annals of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rahul KanadeDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Jack GosdenDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Jonathan RolandDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Mohamed AlyDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Maximilian ReisingerDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Mateusz KachelDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Luigi PirelliDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Koji TakedaDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Michael ArgenzianoDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Hiroo TakayamaDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Arnar GeirssonDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Chunhui WangDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Paul KurlanskyDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Isaac GeorgeDivision of Cardiac, Thoracic & Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mitral annular calcification (MAC) is a chronic and degenerative process, affecting the mitral valve annulus. MAC complicates the decision over the appropriate surgical approach to mitral valve disease. Distorted valvular anatomy increases surgical risk and therefore requires careful patient selection. Here, we report our single-center experience performing mitral valve surgery in the setting of MAC over a 10-year period. Methods: This is a 10-year retrospective analysis of 172 patients with MAC. Sixty-seven patients underwent MAC severity scoring using a 10-point system based on computed tomography (CT). The primary outcome was 30-day mortality, readmission, reoperation, stroke, prolonged ventilation, renal failure and deep sternal infection. Secondary analyses stratified MAC by underlying mitral disease type as well as evaluated outcomes by CT severity score. Patients without MAC undergoing mitral valve replacement surgery during the same time period served as controls. Results: The 30-day mortality was significantly higher in MAC patients compared with non-MAC (9.9% Conclusions: MAC complicates mitral valve surgery, with significant differences seen in survival stroke, renal failure, prolonged ventilatory support, and ICU and hospital length of stay. Careful evaluation of surgical risk and patient selection is warranted in patients with MAC.

Indexed as

echocardiographic outcomesMitral annular calcification (MAC)mitral valve

Identifiers

PMID41383194
PMCPMC12690410

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.