Evidence mapPaperPMID 41383646Full record

ArticleFrontiers in cardiovascular medicine2025

Jingting Yao, Christian T Farrar, Elena Aikawa, David E Sosnovik, Brianna F Moon, Aditi Kulkarni, Jerome L Ackerman

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Update of
    2025
5 · Who and what money

Authors and funding

7 authors.

Jingting YaoAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Christian T FarrarAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Elena AikawaRadiology Department, Harvard Medical School, Boston, MA, United States.
David E SosnovikAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Brianna F MoonAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Aditi KulkarniAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Jerome L AckermanAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.

Funding

MULTIDISCIPLINARY RESEARCH TRAINING IN CARDIOLOGYT32HL007208 · MASSACHUSETTS GENERAL HOSPITAL · 1985 to 2025
$3.9M
Biomedical 600 MHz High Field MR Spectroscopy and Imaging Magnet UpgradeS10OD038220 · MASSACHUSETTS GENERAL HOSPITAL · 2025 to 2025
$2.0M
Bone Quality Assessment with a Novel Three-Bore Magnet Extremity MRI ScannerR01AR075077 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · 2023 to 2025
$1.3M
Nef in impaired efferocytosis: a novel mechanism for vascular disease in HIVR01HL174066 · BRIGHAM AND WOMEN'S HOSPITAL · 2025 to 2025
$740k
NHLBI NIH HHS R01 HL174066NHLBI NIH HHS T32 HL007208NIAMS NIH HHS R01 AR075077NIBIB NIH HHS R01 EB029818NIH HHS S10 OD023406NIH HHS S10 OD038220
6 · The paper itself

Abstract

Aim: Physiological bone mineralization and ectopic vascular calcification share similarities in the composition of calcium phosphate minerals. Evidence suggests a connection between the underlying biological mechanisms driving the deposition of bone mineral and cardiovascular calcification. Therefore, understanding the chemistry and composition of bone mineral and vascular calcification may be important for the development of effective treatments and diagnostic tools for cardiovascular diseases, as pharmacological interventions for the treatment of one process might affect the other. The goal of this study was to identify and compare compositional features of calcium phosphates in bone and calcified vascular tissues using phosphorus-31 ( Methods: Solid state MR spectra were acquired from biological specimens of human trabecular bone ( Results: Solid state Conclusion:

Indexed as

calcium phosphatehydroxyapatitemagnetic resonance spectroscopyplaquevascular calcification

Identifiers

PMID41383646
PMCPMC12689968

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.