Evidence map›Paper›PMID 41383974›Full record

ArticleOncology letters2026

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report.

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou

Abstract readCase Reports
In one paragraph

Article in Oncology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yukun LiGeneral Surgery Department, HuiYa Hospital of The First Affiliated Hospital, Sun Yat-sen University, Huizhou, Guangdong 516200, P.R. China.
Fanchen ZengGeneral Surgery Department, HuiYa Hospital of The First Affiliated Hospital, Sun Yat-sen University, Huizhou, Guangdong 516200, P.R. China.
Zeyao WangGeneral Surgery Department, HuiYa Hospital of The First Affiliated Hospital, Sun Yat-sen University, Huizhou, Guangdong 516200, P.R. China.
Ganjian ZhaoGeneral Surgery Department, HuiYa Hospital of The First Affiliated Hospital, Sun Yat-sen University, Huizhou, Guangdong 516200, P.R. China.
Qi ZhouGeneral Surgery Department, HuiYa Hospital of The First Affiliated Hospital, Sun Yat-sen University, Huizhou, Guangdong 516200, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Castleman disease (CD) is a rare lymphoproliferative disorder that may be complicated by paraneoplastic pemphigus (PNP) and follicular dendritic cell sarcoma (FDCS), although their concurrence is uncommon. The present study reported on a 67-year-old woman with progressive oral ulceration and generalized purple skin spots. Imaging demonstrated a 114mm ×96mm ×118 mm lesion in the left pelvis. Serology was positive for anti-desmoplakin-1 and -3 and anti-BP230 antibodies. Histopathology revealed hyaline-vascular unicentric CD with focal low-to-intermediate-grade FDCS; immunohistochemistry showed CD21, CD23, CD35, CD68, CXCL13 expression and Ki-67 ~10%. Initial therapy comprised high-dose methylprednisolone, intravenous immunoglobulin and thalidomide, followed by surgical resection and adjuvant thalidomide-cyclophosphamide-prednisone. Postoperatively, inflammatory indices normalized and mucocutaneous lesions partially improved; nevertheless, the patient died of respiratory failure 6 months after surgery. In summary, the present case report aimed to provide valuable references and experiences for clinicians in the diagnosis and treatment of CD featuring PNP and FDCS.

Indexed as

Castleman diseasefollicular dendritic cell sarcomaparaneoplastic pemphigus

Identifiers

PMID41383974
PMCPMC12690628

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.