Evidence map›Paper›PMID 41384976›Full record

ArticleSurgery today2026

Comparative outcomes of open and laparoscopic Kasai portoenterostomy for biliary Atresia patients progressing to liver transplantation: A Real-World cohort study.

Yanran Zhang, Yaqiong Qiu, Shuai Wang, Jiaying Liu, Xingyuan Ke, Shaowen Liu, Rongjuan Sun, Yilin Zhao, Xin Li, Shengqiao Zhao and 4 more

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yanran Zhang *Clinical School of Pediatrics, Tianjin Medical University, Tianjin, 300400, China.
Yaqiong Qiu *Clinical School of Pediatrics, Tianjin Medical University, Tianjin, 300400, China.
Shuai Wang *Clinical School of Pediatrics, Tianjin Medical University, Tianjin, 300400, China.
Jiaying LiuClinical School of Pediatrics, Tianjin Medical University, Tianjin, 300400, China.
Xingyuan KeClinical School of Pediatrics, Tianjin Medical University, Tianjin, 300400, China.
Shaowen LiuClinical School of Pediatrics, Tianjin Medical University, Tianjin, 300400, China.
Rongjuan SunClinical School of Pediatrics, Tianjin Medical University, Tianjin, 300400, China.
Yilin ZhaoClinical School of Pediatrics, Tianjin Medical University, Tianjin, 300400, China.
Xin LiClinical School of Pediatrics, Tianjin Medical University, Tianjin, 300400, China.
Shengqiao ZhaoDepartment of Liver Transplantation, Organ Transplantation Center, Tianjin, 300192, China.
Zhixin ZhangDepartment of Liver Transplantation, Organ Transplantation Center, Tianjin, 300192, China.
Xinzhe WeiDepartment of Liver Transplantation, Organ Transplantation Center, Tianjin, 300192, China.
Wei GaoDepartment of Liver Transplantation, Organ Transplantation Center, Tianjin, 300192, China. gaowei_tjfch@163.com.
Jianghua ZhanDepartment of General Surgery, Tianjin Children's Hospital, Tianjin, 300134, China. zhanjianghuatj@163.com.ORCID http://orcid.org/0000-0002-5257-8619

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe compared the long-term outcomes of open (OKPE) versus laparoscopic Kasai portoenterostomy (LKPE) for children with biliary atresia (BA) who ultimately progressed to liver transplantation (LT).

methodsThe subjects of this retrospective multicenter analysis were 276 BA patients (OKPE:225, LKPE:51) undergoing living donor liver transplantation (LDLT) between 2021 and 2023. Propensity score matching (PSM, 51 pairs) and inverse probability treatment weighting (IPTW) balanced the confounders. The time from KPE to LDLT was assessed using Kaplan-Meier curves and Cox regression analysis.

resultsThere were no significant differences in the median time from KPE to LDLT between the OKPE and LKPE groups (228 days vs. 203 days, p = 0.756). Multivariable Cox regression identified patient age at KPE (HR = 1.002, p < 0.01), but not the surgical approach, as a factor influencing the timing of transplantation. No significant differences were observed in postoperative complications, LDLT-free survival rates, or intraoperative transplant metrics between the groups.

conclusionsFor BA infants who progress to LT after KPE, OKPE and LKPE have comparable impact on post-KPE complications, survival time, and outcomes following LT. Thus, the emphasis should be on optimal surgical timing and standardized postoperative management.

Indexed as

Biliary AtresiaLaparoscopyLiver TransplantationPortoenterostomy, HepaticCohort StudiesFemaleHumansInfantLiving DonorsMalePostoperative ComplicationsPropensity ScoreRetrospective StudiesSurvival RateTime FactorsTreatment OutcomeBiliary atresiaKasai portoenterostomyLaparoscopicLiver transplantationReal-world study

Identifiers

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.