Evidence map›Paper›PMID 41385743›Full record

ArticleJMIR aging2025

Digital Isolation and Depression Risk in Older Adults Using the National Health and Aging Trends Study Database: 8-Year Longitudinal Study.

Zhili He, Shijun Yang, Wei Tong, Wei Zhang

Abstract read
In one paragraph

Article in JMIR aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhili HeDepartment of Neurology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Street, Jiang'an District, Wuhan, 430014, China, 86 02765699875.ORCID http://orcid.org/0009-0003-1152-394X
Shijun YangDepartment of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID http://orcid.org/0000-0002-2494-305X
Wei TongDepartment of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID http://orcid.org/0000-0001-8031-0380
Wei ZhangDepartment of Neurology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Street, Jiang'an District, Wuhan, 430014, China, 86 02765699875.ORCID http://orcid.org/0009-0001-4139-0872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The rapid advancement of digital technologies has profoundly transformed communication practices. However, this technological revolution has also led to "digital isolation," a form of social disconnection caused by limited or absent engagement with digital communication tools, including smartphones, computers, email, and the internet. This issue is particularly concerning for older adults, as it may increase their likelihood of developing mental health disorders, with depression being a primary concern. Although digital isolation has been studied less frequently than traditional social isolation, it may be a significant contributor to both the initiation and progression of depression in this population. Objective: This investigation seeks to assess longitudinal relationships between multidimensional digital disengagement (encompassing 4 dimensions: mobile device use, computer interaction, electronic correspondence, and web-based engagement) and incident depression among older adults, using longitudinal data from the nationally representative National Health and Aging Trends Study (NHATS). Methods: The analysis was conducted based on the NHATS dataset, a nationally representative longitudinal survey using multistage sampling to represent community-dwelling Medicare beneficiaries aged 65 years and older in the United States. We analyzed data from 2011 (Round 1) to 2018 (Round 8), including 8199 participants in the discovery and validation cohorts. Digital isolation was measured using a 4-item index based on self-reported nonuse of mobile phones, computers, email, and the internet. Participants were categorized into high (aggregate score ≥3) or low (aggregate score ≤2) digital isolation groups. Weighted Cox regression models with proportional hazards assumptions were used to quantify longitudinal associations between the digital isolation index (and its individual components) and incident depression, incorporating multivariable adjustment for sociodemographic characteristics (age, sex, and race or ethnicity), socioeconomic indicators (education level, family income, and marital status), and clinical profiles (tobacco use history and multimorbidity burden). Time-to-event analyses were visualized through Kaplan-Meier estimators, complemented by prespecified subgroup analyses evaluating effect modification patterns through interaction term testing. Results: A high level of digital isolation, as measured by the composite index, was associated with a significantly greater risk of incident depression (fully adjusted model: hazard ratio 1.35, 95% CI 1.18-1.55; P<.001). Furthermore, analysis of the individual components showed that nonuse of computers, email, and the internet was each significantly associated with a higher depression risk, whereas mobile phone isolation had a weaker, nonsignificant association. Conclusions: The study revealed a robust association between increased digital isolation and a higher likelihood of depression in the older population. These results underscore the importance of implementing tailored public health strategies to address digital isolation, especially for older adults. To minimize its detrimental effects on mental health, policymakers should encourage digital literacy programs and strengthen mental health services.

Indexed as

AgingDepressionSocial IsolationAgedAged, 80 and overDatabases, FactualElectronic MailFemaleHumansLongitudinal StudiesMaleRisk FactorsUnited Statesdepressiondigital isolationlongitudinal cohort studymental healthNational Health and Aging Trends StudyNHATSolder adultspublic health interventionsrisk factorssocial isolationtechnology use

Identifiers

PMID41385743
PMCPMC12700337

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.