ArticleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2026
Gestational diabetes and childhood lung function at age 8 to 9 years in a diverse US cohort.
Article in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundGestational diabetes mellitus (GDM) is associated with systemic processes that may disrupt fetal development and contribute to suboptimal lung function in offspring. Distinct from respiratory conditions such as asthma, lung function is a broad indicator of respiratory health and is predictive of long-term health outcomes. GDM has previously been associated with childhood asthma, but studies on childhood lung function are sparse.
objectiveTo evaluate the association between GDM and respiratory outcomes in children, including lung function, wheeze, and asthma.
methodsWe studied mother-child dyads enrolled in a prospective pregnancy cohort (births 2007-2011) and followed to child age 8 to 9 years. We assessed GDM by chart review and measured child lung function using spirometry, characterizing the following outcomes: forced expiratory volume in 1 second (FEV
resultsGDM was identified in 6% of pregnancies. In children, median (IQR) FEV
conclusionGDM may be a risk factor for decreased lung function and childhood asthma.
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