ArticleScientific reports2025
Phytochemical composition and biological activities of selected essential oils and their discrimination through principal component analysis.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- From Phytochemical Diversity to Clinical Translation: Preparation-Dependent Bioactivity ofInternational journal of molecular sciences · 2026Review
- Article
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3 authors.
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Abstract
The present study aimed to determine the phytochemical characterization, anticancer and antioxidant activities of essential oils (EOs) obtained from nine commonly used medicinal and aromatic plants (MAPs) including Cymbopogon citratus (DC) Stapf (Poaceae), Cistus creticus L. (Cistaceae), Foeniculum vulgare Mill. (Apiaceae), Laurus nobilis L. (Lauraceae), Myrtus communis L. (Myrtaceae), Pinus cembra L. (Pinaceae), Echinacea purpurea (L.) Moench, Helichrysum arenarium (L.) Moench, and Inula viscosa (L.) Aiton (Asteraceae) taxa from Türkiye. The chemical composition of the EOs was identified using gas chromatography-mass spectrometry (GC-MS), and their antioxidant activities were evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) free radical scavenging methods. In addition, the anticancer potential of the EOs were assessed using MTT assay against human cell lines, including hepatocellular carcinoma (HepG2), gastric carcinoma (NCI-N87), breast adenocarcinoma (MCF-7), and human prostate carcinoma (LNCaP clone FGC-Luc2) cancer cells, as well as non-cancerous human umbilical vein endothelial cells (HUVECs). The antioxidant activities of the EOs varied from 35.21 to 79.12%. Consistent with their antioxidant activities, the anticancer activities of the EOs of C. citratus, L. nobilis and, C. creticus exhibited significantly higher anticancer activities compared to the others. However, almost all EOs were found to inhibit cell viability and induce apoptosis in cancer cells. Among the tested concentrations, the highest anticancer activity was observed against against MCF-7 cells, followed by NCI-N87, LNCaP, and HepG2 cancer cells, with the IC
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