ArticleScientific reports2025
Time-series analysis of vitiligo-related online search behavior in response to ambient air pollutants.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
Ambient air pollutants are hazardous materials posing significant risks to global public health. While their impacts on respiratory and cardiovascular systems are well-established, their role in triggering specific autoimmune skin diseases remains under-explored. This study investigates the temporally resolved public health response to air pollutant exposure, using the autoimmune condition vitiligo as a sensitive health endpoint. We aimed to evaluate the differential public health responses to six major air pollutants by analyzing their lagged effects on vitiligo-related online search behavior, using the Baidu Search Index (BSI) as a novel proxy for public concern and health-seeking activity. In this ecological time-series study, we applied a Distributed Lag Non-linear Model (DLNM) to daily data on BSI, air pollutants, and meteorological factors in Changsha, China (2019-2021). The findings reveal distinct, pollutant-specific temporal patterns of public response, suggesting different toxicological pathways. Exposure to industrial pollutants like sulfur dioxide (SO
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