Evidence map›Paper›PMID 41388199›Full record

ReviewInternational journal of clinical oncology2026

Microflora: a promising potential in the diagnosis and treatment of non-small cell lung cancer.

Longfei Wang, Yange Chi, Min Zhang, Jiajun Jiang, Zihui Meng, Zhe Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in International journal of clinical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Longfei Wang *Department of Thoracic Surgery, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Yange Chi *Department of Thoracic Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Min ZhangDepartment of Thoracic Surgery, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Jiajun JiangWuxi School of Medicine, Jiangnan University, Wuxi, China.
Zihui MengDepartment of Research and Development, Wecare Probiotics Co., Ltd., Suzhou, China.
Zhe WangDepartment of Research and Development, Wecare Probiotics Co., Ltd., Suzhou, China. 897358884@qq.com.

Funding

Chinese Youth Medical Innovation Research Projec Phase V
6 · The paper itself

Abstract

The incidence and mortality of non-small cell lung cancer (NSCLC) remain high in China. Recently, several studies have shown a complex correlation between microflora and NSCLC. Compared to patients with healthy/benign lung disease, patients with NSCLC have distinct microflora within the tumor, airways as well as intestines. NSCLC can be diagnosed with the assistance of characteristic microflora and circulating microbial DNA. Microflora changes can affect the efficacy of immunotherapy and treatment-related adverse effects during lung cancer therapy. Modulating microflora imbalance through antibiotics/probiotics nebulization, oral probiotic, prebiotics, and dietary modifications can balance microflora and enhance the effectiveness of immunotherapy. Therefore, microbe-specific testing and targeted therapy have the potential to become a new method in the diagnosis and treatment of NSCLC. This review will explore the molecular mechanisms by which microbes influence lung cancer, and summarize the latest research advances in microbial biomarkers and therapeutic approaches for NSCLC.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsGastrointestinal MicrobiomeHumansImmunotherapyProbioticsDiagnosisImmunotherapyMicrofloraNon-small cell lung cancer

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.