Evidence mapPaperPMID 41388744Full record

SynthesisEndocrinology, diabetes & metabolism2026

Antihypertensive Effects of Curcumin/Turmeric Supplementation in Prediabetes and Diabetes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

Hossein Bahari, Maryam Sharifi, Zahra Nejad Shahrokh Abadi, Mostafa Shahraki Jazinaki, Haniyeh Golafrouz, Zahra Asadi

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Endocrinology, diabetes & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hossein BahariDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0002-3787-2713
Maryam SharifiDepartment of Nutritional Sciences, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Zahra Nejad Shahrokh AbadiThe Countess of Chester NHS Foundation Trust, Chester, UK.
Mostafa Shahraki JazinakiDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0009-0006-6526-8712
Haniyeh GolafrouzRajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-2648-5109
Zahra AsadiStudent Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypertension is a major cardiovascular risk factor in individuals with prediabetes and type 2 diabetes (T2D). Curcumin, with its anti-inflammatory and antioxidant properties, has emerged as a potential adjunct therapy, but its effect on blood pressure in this population remains unclear.

aimsThis meta-analysis aimed to evaluate the effects of curcumin or turmeric supplementation on systolic (SBP) and diastolic (DBP) blood pressure in adults with prediabetes or T2D.

methodsA systematic search of PubMed, Scopus, and Web of Science was conducted until August 2025. Randomised controlled trials (RCTs) investigating curcumin/turmeric supplementation on blood pressure in adults with prediabetes or T2D were included. A meta-analysis was performed using a random-effects model.

resultsFifteen RCTs comprising 16 treatment arms (n = 855 participants) were included. Pooled results indicated that curcumin/turmeric supplementation significantly reduced SBP (WMD: -2.69 mmHg; 95% CI: -3.84 to -1.55; p < 0.001; I

conclusionsCurcumin/turmeric supplementation demonstrates a modest, yet significant reduction in SBP in individuals with prediabetes and diabetes, with a more pronounced effect in those with baseline hypertension. Further high-quality RCTs are needed to confirm these findings and establish optimal dosing.

Indexed as

Antihypertensive AgentsCurcumaCurcuminDiabetes Mellitus, Type 2Dietary SupplementsHypertensionPrediabetic StateBlood PressureHumansRandomized Controlled Trials as TopicAntihypertensive AgentsCurcuminblood pressurecurcumindiabeteshypertensionprediabetesturmeric

Identifiers

PMID41388744
PMCPMC12701325

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.